|
|
|
|
|
Product Name
|
Nav1.5 antibody
|
| |
See all Nav1.5 antibodies (5)...
|
|
Product type
|
Primary antibodies
|
|
Description
|
Goat polyclonal to Nav1.5
|
|
|
Note on antibody grade |
Fast-Track antibodies
- Immunogen affinity purified
- high ELISA titre values
- released early (to accelerate your research)
- 950 Abpoints to the 1st researcher
who submits conclusive data (positive or negative): Read the Fast-Track antibody Terms of Use
|
 |
|
|
Immunogen
|
Synthetic peptide: ETDDQSPEKIN, corresponding to Internal sequence amino acids 1548-1558 of Human Nav1.5 BLAST 'ETDDQSPEKIN' with or 
|
|
Predicted to react
(species key)
|
Hu (Due to sequence homology)
|
|
Specificity
|
This antibody is expected to recognise both reported isoforms (NP_000326 and NP_932173).
|
|
|
Abreviews
|
|
|
|
Application notes
(see key)
|
Recommended dilutions This antibody gave a positive result in ELISA against the immunizing peptide. Antibody detection limit dilution 1:32,000.
Western Blot: Preliminary experiments in ysates of Human Breast and Heart tissues gave no specific signal but low background (at antibody concentration up to 1ug/ml).
Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
|
|
Cellular localization
|
Integral membrane protein
|
|
Research areas
|
Cardiovascular >> Heart >> Cardiac arrhythmias Neuroscience >> Neurotransmission >> Receptors / Channels >> Sodium Channels
|
|
Relevance
|
Nav1.5 is the major cardiac voltage gated sodium channel that is key for normal heart function. It plays a central role in the generation of the cardiac action potential and propagation of electrical impulses in the heart.
|
|
|
|
|
Database links
|
The links below go to external sites and will open in a new browser window
|
|
Raised in
|
Goat
|
|
Clonality
|
Polyclonal
|
|
Isotype
|
IgG
|
|
Purity
|
Immunogen affinity purified
|
|
Storage buffer
|
Preservative: 0.02% Sodium Azide Constituents: 0.5% BSA, Tris saline, pH 7.3 Material safety datasheet (MSDS) for this product: Sodium Azide MSDS
|
|
Purification notes
|
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
|
|
Form
|
Liquid
|
|
Concentration
|
0.500 mg/ml
|
|
Storage instructions
|
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
|
| |
At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Nav1.5 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
 |
|
| |
|
Search PubMed (MEDLINE) for references to Nav1.5
|
| |
Nav1.5 antibody - more information
|
Customer reviews (feedback) regarding Nav1.5 antibody |
Customer FAQs regarding Nav1.5 antibody |
Protocols for Nav1.5 antibody |
Price and availability of products related to Nav1.5 antibody |
| |
Nav1.5 antibody - related products:
|
|
|
| |
Nav1.5 antibody - other tools:
|
Contact Abcam with a Technical Enquiry about Nav1.5 antibody |
| |
All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"