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Product Name 

Nav1.5 antibody

 

See all Nav1.5 antibodies (5)...

Product type 

Primary antibodies

Description 

Goat polyclonal to Nav1.5

 

  Note on antibody grade

Fast-Track antibodies

  • Immunogen affinity purified
  • high ELISA titre values
  • released early (to accelerate your research)
  • 950 Abpoints to the 1st researcher
    who submits conclusive data (positive or negative):
    Read the Fast-Track antibody Terms of Use


Immunogen 

Synthetic peptide: ETDDQSPEKIN, corresponding to Internal sequence amino acids 1548-1558 of Human Nav1.5
BLAST 'ETDDQSPEKIN' with BLAST the sequence with ExPASy or BLAST the sequence with NCBI

Predicted to react 
(species key)

Hu
(Due to sequence homology)

Specificity 

This antibody is expected to recognise both reported isoforms (NP_000326 and NP_932173).


Abreviews 

Customer reviews
(see key)


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Application notes 
(see key)

Recommended dilutions
This antibody gave a positive result in ELISA against the immunizing peptide. Antibody detection limit dilution 1:32,000.

Western Blot: Preliminary experiments in ysates of Human Breast and Heart tissues gave no specific signal but low background (at antibody concentration up to 1ug/ml).

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Integral membrane protein

Research areas 

Cardiovascular >> Heart >> Cardiac arrhythmias
Neuroscience >> Neurotransmission >> Receptors / Channels >> Sodium Channels

Relevance 

Nav1.5 is the major cardiac voltage gated sodium channel that is key for normal heart function. It plays a central role in the generation of the cardiac action potential and propagation of electrical impulses in the heart.

 

Alternative names Nav1.5 antibody (ab39992)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

6331    (Human)

GeneCard

    

GC03M038565    (Human)

Omim

    

600163    (Human)

SwissProt

    

Q14524    (Human)
Q86V90    (Human)
Q96J69    (Human)

Unigene

    

517898    (Human)

Raised in 

Goat

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Immunogen affinity purified

Storage buffer 

Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris saline, pH 7.3

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Purification notes 

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Form 

Liquid

Concentration 

0.500 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Nav1.5 antibody is on this datasheet. But please do contact us if you would like any reassurance!


 

Search PubMed (MEDLINE) for references to Nav1.5

 

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