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Western blot - Neuropilin 1 antibody (ab25998)
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Product Name
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Neuropilin 1 antibody
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See all Neuropilin 1 antibodies (7)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to Neuropilin 1
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Immunogen
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Synthetic peptide, coupled to carrier protein, corresponding to amino acids within the N-terminal CUB domain of human Neuropilin 1. This sequence is highly conserved in rat and mouse Neuropilin 1.
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Reacts with
(species key)
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Hu, Ms
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Specificity
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ab25998 is specific for Neuropilin 1. Immunogen sequence has low homology to Neuropilin 2.
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Tested applications
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ELISA, WB
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Abreviews
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Application notes
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Recommended dilutions
ELISA: 1/2000.
WB: 1/500. Detects a band of approximately 130 kDa (predicted molecular weight: 102 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Cell Membrane; Single-pass type I membrane protein. Secreted (Isoform 2).
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Research areas
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Immunology >> Adaptive Immunity >> Regulatory T Cells
Neuroscience >> Neurology process >> Growth and Development >> Axonal Guidance Proteins
Cardiovascular >> Angiogenesis >> Growth Factors >> VEGF >> VEGF Receptors
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Relevance
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Neuropilin 1 is a membrane-bound coreceptor to a tyrosine kinase receptor for both Vascular Endothelial Growth Factor and Semaphorin family members. Neuropilin 1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration, and invasion.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.05% Sodium Azide
Constituents: 50% Glycerol, PBS, 1mg/ml BSA Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Neuropilin 1 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for Neuropilin 1 antibody images, references, products related to ab25998 and other tools.
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Neuropilin 1 antibody images:
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 Western blot - Neuropilin 1 antibody (ab25998)
All lanes : Neuropilin 1 antibody (ab25998) at 1/500 dilution
Lane 1 : Untransfected COS-7 cells
Lane 2 : COS-7 cells transfected with HA-tagged Neuropilin 1
Predicted band size : 102 kDa
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References for Neuropilin 1 antibody (ab25998)
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This product has been used in: (two most recent references)
Joseph D et al. Hormonal regulation and distinct functions of semaphorin-3B and semaphorin-3F in ovarian cancer. Mol Cancer Ther 9:499-509 (2010). WB; Human. PubMed: 20124444
Korgaonkar SN et al. HIV-1 upregulates VEGF in podocytes. J Am Soc Nephrol 19:877-83 (2008). PubMed: 18443354
See all 3 publication references for this product.
If you publish research using ab25998 please let us know so that we can cite the reference on this datasheet.
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Search PubMed (MEDLINE) for references to Neuropilin 1
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Neuropilin 1 antibody - more information
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Customer reviews (feedback) regarding Neuropilin 1 antibody |
Customer FAQs regarding Neuropilin 1 antibody |
Protocols for Neuropilin 1 antibody |
Price and availability of products related to Neuropilin 1 antibody |
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Neuropilin 1 antibody - related products:
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Neuropilin 1 antibody - other tools:
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Contact Abcam with a Technical Enquiry about Neuropilin 1 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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