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Anti-NuMA antibody [A73-B/D12] (ab5675)

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Overview

Product name

Anti-NuMA antibody [A73-B/D12]
See all NuMA products (8) ...

Description

Mouse monoclonal [A73-B/D12] to NuMA

Specificity

Reacts with an intracellular 228 kD protein found in the nucleus during interphase.

Tested applications

IP, IHC-Fr, IHC-P, WBmore details

Cross reactivity

Reacts with

Human

Immunogen

Live Ls 174T cells (human colon carcinoma).

Positive control

Tonsil, Thymus, Spleen.

Properties

Form

Liquid

Storage instructions

Store at +4°C. Do not freeze.

Storage buffer

pH: 7.40
Preservative: 0.1% Sodium azide
Constituent: PBS

Concentration

Concentration information loading...

Purity

Protein G purified

Clonality

Monoclonal

Clone number

A73-B/D12

Isotype

IgM

Research areas

Cell Biology >> Cell Cycle >> Cell Division >> Spindle
Cell Biology >> Cell Cycle >> Markers

Applications

Show applications key

Our Abpromise guarantee covers the use of ab5675 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Function

May be a structural component of the nucleus.

Cellular localization

Nucleus. Chromosome. Dissociates from condensing chromosomes during early prophase, before the complete disintegration of the nuclear lamina. As mitosis progresses it reassociates with telophase chromosomes very early during nuclear reformation, before substantial accumulation of lamins on chromosomal surfaces is evident.

Target information above from: UniProt accessionQ14980 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • Centrophilin stabilizes mitotic spindle in mitotic cells antibody
  • Nuclear Mitotic Apparatus Protein antibody
  • Nuclear mitotic apparatus protein 1 antibody
  • NUMA 1 antibody
  • NUMA antibody
  • NuMA protein antibody
  • NUMA1 antibody
  • NUMA1_HUMAN antibody
  • SP H antigen antibody
  • SP-H antigen antibody
  • Structural nuclear protein antibody
see all

Database links

References for Anti-NuMA antibody [A73-B/D12] (ab5675)

This product has been referenced in:

  • Kwong Jet al. An antagonist of the chemokine receptor CXCR4 induces mitotic catastrophe in ovarian cancer cells. Mol Cancer Ther 8:1893-905 (2009).Read more (PubMed: 19567818) »

See 1 publication for this product

Publishing research using ab5675? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"