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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - NuMA antibody (ab84680)
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - NuMA antibody (ab84680)
(enlarge)
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - NuMA antibody (ab84680)
(enlarge)
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Product Name
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NuMA antibody
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See all NuMA antibodies (6)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to NuMA
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Immunogen
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Synthetic peptide corresponding to a region between residue 900 and 950 of Human NuMA (NP_006176.2).
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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IHC-P
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Abreviews
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Application notes
(see key)
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Recommended dilutions
IHC-P: 1/100 - 1/500.
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Human Anaplastic Thyroid Carcinoma, Breast Carcinoma, Colon Carcinoma, Linitis Plastica Stomach Cancer, Lung Adenocarcinoma, Ovarian Carcinoma, Pancreatic Islet Cell Tumor, Prostate Carcinoma, Skin Basal Cell Carcinoma, Skin Melanoma, Stomach Adenocarcinoma and Testicular Seminoma.
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Cellular localization
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Nuclear
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Research areas
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Cell Biology >> Cell Cycle >> Cell Division >> Spindle
Cell Biology >> Cell Cycle >> Markers
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Relevance
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NuMA (Nuclear Mitotic Apparatus Protein) is an intranuclear protein and present in nucleus during interphase. At the onset of mitosis, it redistributes from the nucleus to two centrosomal structures that later will become part of the mitotic spindle pole. After anaphase, the protein redistributes from the spindle polar region into reforming nucleus. NuMA is an essential protein during mitosis for the terminal phases of chromosome separation and/or nuclear reassembly. Recently a study shows that NuMA is cleaved to a 180 to 200kDa during apoptosis.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.09% Sodium Azide
Constituents: 0.1% BSA, Tris buffered saline Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Storage instructions
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Store at +4°C.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this NuMA antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for NuMA antibody images, references, products related to ab84680 and other tools.
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NuMA antibody images:
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 Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - NuMA antibody (ab84680)
ab84680, at 1/100 dilution, staining NuMA in formalin-fixed, paraffin-embedded human breast carcinoma by Immunohistochemistry using a Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed Hilyte PlusTM 555 secondary antibody at a dilution of 1/100.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - NuMA antibody (ab84680)
ab84680, at 1/250 dilution, staining NuMA in formalin-fixed, paraffin-embedded human breast carcinoma by Immunohistochemistry using DAB staining.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - NuMA antibody (ab84680)
ab84680, at 1/250 dilution, staining NuMA in formalin-fixed, paraffin-embedded human seminoma by Immunohistochemistry using DAB staining.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - NuMA antibody (ab84680)
ab84680, at 1/250 dilution, staining NuMA in formalin-fixed, paraffin-embedded human ovarian tumor by Immunohistochemistry using DAB staining.
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Search PubMed (MEDLINE) for references to NuMA
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NuMA antibody - more information
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Customer reviews (feedback) regarding NuMA antibody |
Customer FAQs regarding NuMA antibody |
Protocols for NuMA antibody |
Price and availability of products related to NuMA antibody |
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NuMA antibody - related products:
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NuMA antibody - other tools:
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Contact Abcam with a Technical Enquiry about NuMA antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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