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Nucleobindin 1 Precursor protein (Tagged) (ab132326)

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Overview

  • Product nameNucleobindin 1 Precursor protein (Tagged)
  • Protein descriptionRecombinant full length Human Nucleobindin 1 Precursor (amino acids 28-461) with N terminal proprietary tag; Predicted MWt 73.48 kDa inclusive of tag.
  • Uniprot accessionQ02818
  • Molecular weight73.480kDa inclusive of tags
  • Protein length434 amino acids
  • Expression hostWheat germ

    • Properties

  • FormLiquid
  • Storage instructionsShipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
  • Storage bufferpH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl
  • Concentration information loading...
  • Sequence notesPLERGAPNKEETPATESPDTGLYYHRYLQEVIDVLETDGH FREKLQAANAEDIKSGKLSRELDFVSHHVRTKLDELERQE VSRPRMLLKAKMDAEQDPNVQVDHLNLLKQFEHLDPQNQH TFEARDLELLIQTATRDLAQYDAAHHEEFKRYEMLKEHER RRYLESLGEEQRKEAERKLEEQQRRHREHPKVNVPGSQAQ LKEVWEELDGLDPNRFNPKTFFILHDINSDGVLDEQELEA LFTKELEKVYDPKNEEDDMREMEEERLRMREHVMKNVDTN QDRLVTLEEFLASTQRKEFGDTGEGWETVEMHPAYTEEEL RRFEEELAAREAELNAKAQRLSQETEALGRSQGRLEAQKR ELQQAVLHMEQRKQQQQQQQGHKAPAAHPEGQLKFHPDTD DVPVPAPAGDQKEVDTSEKKLLERLPEVEVPQHL
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab132326 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    WB WB: Use at an assay dependent concentration.
    SDS-PAGE SDS-PAGE: Use at an assay dependent concentration.
    ELISA ELISA: Use at an assay dependent concentration.
  • Application notesThis peptide can be used with studies using ab154262.

    • Protein info

    • Alternative names
        CALNUCHGNC:8043NUC
        NUCB1NUCB1_HUMANNucleobindin-1
      see all
  • FunctionMajor calcium-binding protein of the Golgi. May have a role in calcium homeostasis.
  • Tissue specificityExpressed both in fetal and adult heart, lung, liver, kidney and brain, and in adult skeletal muscle, placenta and pancreas.
  • Sequence similaritiesBelongs to the nucleobindin family.
    Contains 2 EF-hand domains.
  • DomainThe EF-hand domains are unfolded in the absence of Ca(2+) and fold upon Ca(2+) addition.
  • Post-translational
    modifications    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationGolgi apparatus > cis-Golgi network membrane. Cytoplasm. A small fraction of the protein may be cytoplasmic.

    • Target information above from: UniProt accession Q02818 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    Nucleobindin 1 Precursor protein (Tagged) images

    • SDS-PAGE - Nucleobindin 1 Precursor protein (Tagged) (ab132326)
      SDS-PAGE - Nucleobindin 1 Precursor protein (Tagged) (ab132326)
      12.5% SDS-PAGE analysis of ab132326 stained with Coomassie Blue.

    References for Nucleobindin 1 Precursor protein (Tagged) (ab132326)

    ab132326 has not yet been referenced specifically in any publications.

    Publishing research using ab132326 ? Please let us know so that we can cite the reference in this datasheet

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