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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - OAS2 antibody (ab60091)
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Product Name
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OAS2 antibody
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See all OAS2 antibodies (2)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to OAS2
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Immunogen
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Synthetic peptide (10-30 aa in length) at the C-term of last 50 aa of human OAS2 conjugated to KLH
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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ELISA, IHC-P
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: 1/1000.
IHC-P: 1/50 - 1/100.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Human breast carcinoma tissue.
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Cellular localization
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Mitochondrion. Nucleus. Microsome. Note=Associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions.
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Research areas
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Chromatin and Nuclear Signaling >> Chromatin Binding Proteins >> DNA / RNA binding
Chromatin and Nuclear Signaling >> DNA / RNA >> RNA Processing >> Other
Immunology >> Innate Immunity >> Cytokines >> Interferons
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Relevance
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OAS2 is an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced by interferons and catalyzes the 2', 5' oligomers of adenosine in order to bind and activate RNase L. This enzyme family plays a significant role in the inhibition of cellular protein synthesis and viral infection resistance.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Protein G purified
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Storage buffer
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Preservative: 0.09% Sodium Azide
Constituents: PBS Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Purification notes
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ab60091 is purified through a protein G column and eluted out with both high and low pH buffers and neutralized immediately after elution then followed by dialysis against PBS.
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Form
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Liquid
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Concentration
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0.250 mg/ml
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this OAS2 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for OAS2 antibody images, references, products related to ab60091 and other tools.
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OAS2 antibody images:
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 Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - OAS2 antibody (ab60091)
ab60091 at 1/50 - 1/100 dilution, staining OAS2 in human breast carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue, followed by peroxidase-conjugated secondary antibody and AEC staining.
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Search PubMed (MEDLINE) for references to OAS2
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OAS2 antibody - more information
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Customer reviews (feedback) regarding OAS2 antibody |
Customer FAQs regarding OAS2 antibody |
Protocols for OAS2 antibody |
Price and availability of products related to OAS2 antibody |
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OAS2 antibody - related products:
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OAS2 antibody - other tools:
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Contact Abcam with a Technical Enquiry about OAS2 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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