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Anti-OAS2 antibody (ab60091)

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Overview

Product name

Anti-OAS2 antibody
See all OAS2 products (2) ...

Description

Rabbit polyclonal to OAS2

Tested applications

ELISA, IHC-Pmore details

Cross reactivity

Reacts with

Human

Immunogen

Synthetic peptide (10-30 aa in length) at the C-term of last 50 aa of human OAS2 conjugated to KLH

Positive control

Human breast carcinoma tissue.

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 0.09% Sodium Azide
Constituents: PBS

Concentration

Concentration information loading...

Purity

Protein G purified

Purification notes

ab60091 is purified through a protein G column and eluted out with both high and low pH buffers and neutralized immediately after elution then followed by dialysis against PBS.

Clonality

Polyclonal

Isotype

IgG

Research areas

Epigenetics and Nuclear Signaling >> Chromatin Binding Proteins >> DNA / RNA binding
Epigenetics and Nuclear Signaling >> DNA / RNA >> RNA Processing >> Other
Immunology >> Innate Immunity >> Cytokines >> Interferons

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - OAS2 antibody (ab60091)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - OAS2 antibody (ab60091) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab60091 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ELISA

     ELISA: 1/1000

    ELISA: 1/1000

  • 1 Image

    IHC-P

     IHC-P: 1/50 - 1/100.

    IHC-P: 1/50 - 1/100.

Target

Relevance

OAS2 is an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced by interferons and catalyzes the 2', 5' oligomers of adenosine in order to bind and activate RNase L. This enzyme family plays a significant role in the inhibition of cellular protein synthesis and viral infection resistance.

Cellular localization

Mitochondrion. Nucleus. Microsome. Note=Associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions.

Alternative names

  • (2-5')oligo(A) synthetase 2 antibody
  • 2'-5'-oligoadenylate synthetase 2 antibody
  • 2'-5'-oligoadenylate synthetase 2, 69/71kDa antibody
  • 2-5A synthetase 2 antibody
  • MGC78578 antibody
  • p69 OAS / p71 OAS antibody
  • p69OAS / p71OAS antibody
see all

Database links

Anti-OAS2 antibody images:

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - OAS2 antibody (ab60091)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - OAS2 antibody (ab60091)

ab60091 at 1/50 - 1/100 dilution, staining OAS2 in human breast carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue, followed by peroxidase-conjugated secondary antibody and AEC staining.

References for Anti-OAS2 antibody (ab60091)

ab60091 has not yet been referenced specifically in any publications.

Publishing research using ab60091? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"