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Anti-OAS2 antibody (ab90045)

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Overview

Product name

Anti-OAS2 antibody
See all OAS2 products (2) ...

Description

Rabbit polyclonal to OAS2

Tested applications

WBmore details

Cross reactivity

Reacts with

Human

Predicted to work with

Rat, Cow, Dog, Pig, Chimpanzee

Immunogen

Synthetic peptide corresponding to a region from N terminal amino acids 36-85 (EMVNTICDVLQEPEQFPLVQGVAIGGSYGRKTVLRGNSD GTLVLFFSDLK) of Human OAS2 (NP_002526).

EMVNTICDVL QEPEQFPLVQ GVAIGGSYGR KTVLRGNSDG TLVLFFSDLK

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Positive control

SH SYSY cell lysate

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: 2% Sucrose, PBS

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Clonality

Polyclonal

Isotype

IgG

Research areas

Epigenetics and Nuclear Signaling >> Chromatin Binding Proteins >> DNA / RNA binding
Epigenetics and Nuclear Signaling >> DNA / RNA >> RNA Processing >> Other
Immunology >> Innate Immunity >> Cytokines >> Interferons

  • Western blot - OAS2 antibody (ab90045)Western blot - OAS2 antibody (ab90045) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab90045 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

OAS2 is an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced by interferons and catalyzes the 2', 5' oligomers of adenosine in order to bind and activate RNase L. This enzyme family plays a significant role in the inhibition of cellular protein synthesis and viral infection resistance.

Cellular localization

Mitochondrion. Nucleus. Microsome. Note=Associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions.

Alternative names

  • 2-5A synthetase 2 antibody
  • MGC78578 antibody
  • p69 OAS / p71 OAS antibody
  • p69OAS / p71OAS antibody

Database links

Anti-OAS2 antibody images:

  Western blot - OAS2 antibody (ab90045)

Western blot - OAS2 antibody (ab90045)

Anti-OAS2 antibody (ab90045) at 1 µg/ml (5% skim milk / PBS buffer) + SH SYSY cell lysate at 10 µg

Secondary
HRP conjugated anti-Rabbit IgG at 1/50000 dilution

Predicted band size : 79 kDa


Gel concentration: 12%

References for Anti-OAS2 antibody (ab90045)

ab90045 has not yet been referenced specifically in any publications.

Publishing research using ab90045? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"