|
|
|
|
Western blot - OAS2 antibody (ab90045)
(enlarge)
|
|
|
|
|
Product Name
|
OAS2 antibody
|
| |
See all OAS2 antibodies (2)...
|
|
Product type
|
Primary antibodies
|
|
Description
|
Rabbit polyclonal to OAS2
|
|
Immunogen
|
Synthetic peptide corresponding to a region from N terminal amino acids 36-85 (EMVNTICDV LQEPEQFPLV QGVAIGGSYG RKTVLRGNSD GTLVLFFSDL of Human OAS2 (NP_002526).
BLAST 'EMVNTICDVL QEPEQFPLVQ GVAIGGSYGR KTVLRGNSDG TLVLFFSDLK ' with  or 
|
|
Reacts with
(species key)
|
Hu
|
|
Tested applications
(see key)
|
WB
|
|
|
Abreviews
|
|
|
|
Application notes
(see key)
|
Recommended dilutions
WB: Use at a concentration of 1 µg/ml. Predicted molecular weight: 79 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
|
|
Positive control
(see definition)
|
SH SYSY cell lysate
|
|
Cellular localization
|
Mitochondrion. Nucleus. Microsome. Note=Associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions.
|
|
Research areas
|
Chromatin and Nuclear Signaling >> Chromatin Binding Proteins >> DNA / RNA binding
Chromatin and Nuclear Signaling >> DNA / RNA >> RNA Processing >> Other
Immunology >> Innate Immunity >> Cytokines >> Interferons
|
|
Relevance
|
OAS2 is an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced by interferons and catalyzes the 2', 5' oligomers of adenosine in order to bind and activate RNase L. This enzyme family plays a significant role in the inhibition of cellular protein synthesis and viral infection resistance.
|
|
|
|
|
Database links
|
The links below go to external sites and will open in a new browser window |
|
Raised in
|
Rabbit
|
|
Clonality
|
Polyclonal
|
|
Isotype
|
IgG
|
|
Purity
|
Immunogen affinity purified
|
|
Storage buffer
|
Preservative: None
Constituents: 2% Sucrose, PBS
|
|
Form
|
Liquid
|
|
Concentration
|
1.000 mg/ml
|
|
Storage instructions
|
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
|
| |
At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this OAS2 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
 |
|
|
See below for OAS2 antibody images, references, products related to ab90045 and other tools.
|
| |
OAS2 antibody images:
|
 Western blot - OAS2 antibody (ab90045)
OAS2 antibody (ab90045) at 1 µg/ml (5% skim milk / PBS buffer) + SH SYSY cell lysate at 10 µg
Secondary
HRP conjugated anti-Rabbit IgG at 1/50000 dilution
Predicted band size : 79 kDa
Gel concentration: 12%
|
| |
| |
|
Search PubMed (MEDLINE) for references to OAS2
|
| |
OAS2 antibody - more information
|
Customer reviews (feedback) regarding OAS2 antibody |
Customer FAQs regarding OAS2 antibody |
Protocols for OAS2 antibody |
Price and availability of products related to OAS2 antibody |
| |
OAS2 antibody - related products:
|
|
|
| |
OAS2 antibody - other tools:
|
Contact Abcam with a Technical Enquiry about OAS2 antibody |
| |
All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Pricing information loading
