Anti-OASL antibody (ab86124)

Overview

• Product nameAnti-OASL antibodySee all OASL primary antibodies ...
• Description
  Rabbit polyclonal to OASL
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Human
  Predicted to work with: Mouse, Rat, Cow, Pig
• Immunogen

  Synthetic peptide corresponding to a region within the N terminal amino acids 35-84 (AVRTVEEFLRQEHFQGKRGLDQDVRVLKVVKVGSFGNGT VLRSTREVELV) of Human OASL, NP_937856

• Positive controlFetal brain lysate (Human)

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Storage bufferPreservative: None
  Constituents: 2% Sucrose, PBS
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Immunology
  • Innate Immunity
  • Cytokines
  • Interferons

  • Cell Biology
  • Other Antibodies
  • Other Antibodies

Applications

Target

• FunctionDoes not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L.
• Tissue specificityExpressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis.
• Sequence similaritiesBelongs to the 2-5A synthase family.
  Contains 2 ubiquitin-like domains.
• DomainThe ubiquitin-like domains are essential for its antiviral activity.
• Cellular localizationCytoplasm and Nucleus > nucleolus. Cytoplasm.

Target information above from: UniProt accession Q15646 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 8638 Human
  • Entrez Gene: 8638 Human
  • Entrez Gene: 23962 Mouse
  • Entrez Gene: 595119 Pig
  • Omim: 603281 Human
  • SwissProt: Q15646 Human
  • SwissProt: Q15646 Human
  • SwissProt: Q9Z2F2 Mouse

  • SwissProt: Q8VI94 Mouse
  • SwissProt: G3V645 Rat
  • SwissProt: Q5MYT9 Rat
  • Unigene: 118633 Human

  see all

• Alternative names
  2' 5' oligoadenylate synthetase like antibody2''-5''-OAS-related protein antibody2''-5''-OAS-RP antibody

  2''-5''-oligoadenylate synthase-like protein antibody2'-5' oligoadenylate synthetase-like 2 antibody2'-5'-oligoadenylate synthetase-like antibody59 kDa 2' 5' oligoadenylate synthetase like protein antibody59 kDa 2''-5''-oligoadenylate synthase-like protein antibody59 kDa 2'-5'-oligoadenylate synthetase-like protein antibodyM1204 antibodyMmu-OASL antibodyOASL antibodyOASL_HUMAN antibodyOasl2 antibodyp59 OASL antibodyp59OASL antibodyTHYROID HORMONE RECEPTOR INTERACTOR 14 antibodyThyroid receptor interacting protein 14 antibodyThyroid receptor-interacting protein 14 antibodyTR-interacting protein 14 antibodyTRIP-14 antibodyTRIP14 antibody

  see all

Anti-OASL antibody images

• 

  Western blot - OASL antibody (ab86124)
  Anti-OASL antibody (ab86124) at 1 µg/ml + Fetal brain lysate (Human) at 10 µg
  
  Secondary
  HRP conjugated anti-Rabbit IgG at 1/50000 dilution
  
  Predicted band size : 59 kDa
  Additional bands at : 27 kDa. We are unsure as to the identity of these extra bands.