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Western blot - OASL antibody (ab86124)
Western blot - OASL antibody (ab86124)
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Product Name 

OASL antibody

 

See all OASL antibodies (2)...

Product type 

Primary antibodies

Description 

Rabbit polyclonal to OASL

Immunogen 

Synthetic peptide corresponding to a region within the N terminal amino acids 35-84 (AVRTVEEFL RQEHFQGKRG LDQDVRVLKV VKVGSFGNGT VLRSTREVEL of Human OASL, NP_937856

Reacts with 
(species key)

Hu

Tested applications 
(see key)

WB


Abreviews 

Customer reviews
(see key)


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Application notes 
(see key)

Recommended dilutions
WB: Use at a concentration of 1 µg/ml. Predicted molecular weight: 59 kDa.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

Fetal brain lysate (Human)

Cellular localization 

Cytoplasmic and Nuclear

Research areas 

Cell Biology >> Other Antibodies >> Other Antibodies
Immunology >> Innate Immunity >> Cytokines >> Interferons

Relevance 

2-prime,5-prime oligoadenylates (2-5As) bind to and activate RNase L, leading to degradation of RNA and inhibition of protein synthesis. 2-5As are produced by 2-5A synthetases (OASs), a highly-conserved family of interferon-induced enzymes. The predicted 514-amino acid human p59OASL (2-5A synthetases-like) protein shares a highly conserved N-terminal domain with other OASs. The C-terminal portion of p59OASL contains 2 ubiquitin-like domains. p59OASL is expressed in most tissues, with the highest levels in hematopoietic tissues, colon, and stomach.

 

OASL antibody (ab86124)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

8638    (Human)

GeneCard

    

GC12M119920    (Human)

Omim

    

603281    (Human)

SwissProt

    

Q15646    (Human)
Q17R95    (Human)

Unigene

    

118633    (Human)

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Immunogen affinity purified

Storage buffer 

Preservative: None
Constituents: 2% Sucrose, PBS

Form 

Lyophilised
Add 50 µl of distilled water. Final antibody concentration is 1 mg/ml.

Concentration 

1.000 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this OASL antibody is on this datasheet. But please do contact us if you would like any reassurance!


See below for OASL antibody images, references, products related to ab86124 and other tools.

 

OASL antibody images:

Product image  Western blot - OASL antibody (ab86124)

Western blot - OASL antibody (ab86124)

OASL antibody (ab86124) at 1 µg/ml + Fetal brain lysate (Human) at 10 µg

Secondary
HRP conjugated anti-Rabbit IgG at 1/50000 dilution

Predicted band size : 59 kDa
Additional bands at : 27 kDa. We are unsure as to the identity of these extra bands.

Gel concentration: 12%

 
 

Search PubMed (MEDLINE) for references to OASL

 

OASL antibody - more information

Customer reviews (feedback) regarding OASL antibody

Customer FAQs regarding OASL antibody

Protocols for OASL antibody

Price and availability of products related to OASL antibody

 

OASL antibody - related products:

Products for Western blot

Loading controls

Lysates

 

Positive Controls for OASL antibody

ab29467

  

Brain (Human) Tissue Lysate - fetal normal tissue

 

Compatible Secondaries for OASL antibody

ab6564

  

Cy5 ® antibody

ab6717

  

FITC antibody

ab6720

  

Biotin antibody

ab6721

  

HRP antibody

ab6722

  

Alkaline Phosphatase antibody

ab6793

  

Texas Red ® antibody

ab7007

  

Phycoerythrin antibody

ab7019

  

Agarose antibody

ab27234

  

10nm Gold antibody

ab27235

  

5nm Gold antibody

ab27236

  

15nm Gold antibody

ab27237

  

20nm Gold antibody

ab27238

  

30nm Gold antibody

ab27239

  

10nm Gold antibody

ab27240

  

5nm Gold antibody

ab31193

  

Duck polyclonal to Rabbit IgG

ab60314

  

Chromeo™ 488 antibody

ab60315

  

Chromeo™ 494 antibody

ab60317

  

Chromeo™ 546 antibody

ab60319

  

Chromeo™ 642 antibody

 

Other OASL Antibodies

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OASL antibody - other tools:

Contact Abcam with a Technical Enquiry about OASL antibody

 

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