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Anti-OASL antibody (ab86124)

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Overview

Product name

Anti-OASL antibody
See all OASL products (2) ...

Description

Rabbit polyclonal to OASL

Tested applications

WBmore details

Cross reactivity

Reacts with

Human

Predicted to work with

Mouse, Rat, Cow, Pig

Immunogen

Synthetic peptide corresponding to a region within the N terminal amino acids 35-84 (AVRTVEEFLRQEHFQGKRGLDQDVRVLKVVKVGSFGNGT VLRSTREVELV) of Human OASL, NP_937856

Positive control

Fetal brain lysate (Human)

Properties

Form

Lyophilised:
Add 50 µl of distilled water. Final antibody concentration is 1 mg/ml.

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: 2% Sucrose, PBS

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Clonality

Polyclonal

Isotype

IgG

  • Western blot - OASL antibody (ab86124)Western blot - OASL antibody (ab86124) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab86124 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

2-prime,5-prime oligoadenylates (2-5As) bind to and activate RNase L, leading to degradation of RNA and inhibition of protein synthesis. 2-5As are produced by 2-5A synthetases (OASs), a highly-conserved family of interferon-induced enzymes. The predicted 514-amino acid human p59OASL (2-5A synthetases-like) protein shares a highly conserved N-terminal domain with other OASs. The C-terminal portion of p59OASL contains 2 ubiquitin-like domains. p59OASL is expressed in most tissues, with the highest levels in hematopoietic tissues, colon, and stomach.

Cellular localization

Cytoplasmic and Nuclear

Alternative names

  • p59 OASL antibody
  • 2' 5' oligoadenylate synthetase like antibody
  • 2'-5' oligoadenylate synthetase-like 2 antibody
  • 2'-5'-oligoadenylate synthetase-like antibody
  • 59 kDa 2' 5' oligoadenylate synthetase like protein antibody
  • 59 kDa 2'-5'-oligoadenylate synthetase-like protein antibody
  • M1204 antibody
  • Mmu-OASL antibody
  • Oasl2 antibody
  • p59OASL antibody
  • THYROID HORMONE RECEPTOR INTERACTOR 14 antibody
  • Thyroid receptor interacting protein 14 antibody
  • Thyroid receptor-interacting protein 14 antibody
  • TRIP-14 antibody
  • TRIP14 antibody
see all

Anti-OASL antibody images:

  Western blot - OASL antibody (ab86124)

Western blot - OASL antibody (ab86124)

Anti-OASL antibody (ab86124) at 1 µg/ml + Fetal brain lysate (Human) at 10 µg

Secondary
HRP conjugated anti-Rabbit IgG at 1/50000 dilution

Predicted band size : 59 kDa
Additional bands at : 27 kDa. We are unsure as to the identity of these extra bands.

Gel concentration: 12%

References for Anti-OASL antibody (ab86124)

ab86124 has not yet been referenced specifically in any publications.

Publishing research using ab86124? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"