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Western blot - OASL antibody (ab86124)
(enlarge)
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Product Name
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OASL antibody
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See all OASL antibodies (2)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to OASL
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Immunogen
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Synthetic peptide corresponding to a region within the N terminal amino acids 35-84 (AVRTVEEFL RQEHFQGKRG LDQDVRVLKV VKVGSFGNGT VLRSTREVEL of Human OASL, NP_937856
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: Use at a concentration of 1 µg/ml. Predicted molecular weight: 59 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Fetal brain lysate (Human)
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Cellular localization
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Cytoplasmic and Nuclear
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Research areas
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Cell Biology >> Other Antibodies >> Other Antibodies
Immunology >> Innate Immunity >> Cytokines >> Interferons
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Relevance
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2-prime,5-prime oligoadenylates (2-5As) bind to and activate RNase L, leading to degradation of RNA and inhibition of protein synthesis. 2-5As are produced by 2-5A synthetases (OASs), a highly-conserved family of interferon-induced enzymes. The predicted 514-amino acid human p59OASL (2-5A synthetases-like) protein shares a highly conserved N-terminal domain with other OASs. The C-terminal portion of p59OASL contains 2 ubiquitin-like domains. p59OASL is expressed in most tissues, with the highest levels in hematopoietic tissues, colon, and stomach.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: None
Constituents: 2% Sucrose, PBS
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Form
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Lyophilised
Add 50 µl of distilled water. Final antibody concentration is 1 mg/ml.
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this OASL antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for OASL antibody images, references, products related to ab86124 and other tools.
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OASL antibody images:
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 Western blot - OASL antibody (ab86124)
OASL antibody (ab86124) at 1 µg/ml + Fetal brain lysate (Human) at 10 µg
Secondary
HRP conjugated anti-Rabbit IgG at 1/50000 dilution
Predicted band size : 59 kDa
Additional bands at : 27 kDa. We are unsure as to the identity of these extra bands.
Gel concentration: 12%
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Search PubMed (MEDLINE) for references to OASL
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OASL antibody - more information
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Customer reviews (feedback) regarding OASL antibody |
Customer FAQs regarding OASL antibody |
Protocols for OASL antibody |
Price and availability of products related to OASL antibody |
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OASL antibody - related products:
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OASL antibody - other tools:
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Contact Abcam with a Technical Enquiry about OASL antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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