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Overview
Product name
Anti-OBFC1 antibody
See all OBFC1 products (4) ...
Description
Mouse monoclonal to OBFC1
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Recombinant full length protein, corresponding to amino acids 1-272 of Human OBFC1
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG2a
Light chain type
kappa
Research areas
Epigenetics and Nuclear Signaling >> Chromatin Binding Proteins >> DNA / RNA binding
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Western blot - OBFC1 antibody (ab57764)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab57764 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: Use at a concentration of 1-5 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.
Sequence similarities
Belongs to the STN1 family.
Contains 1 OB DNA-binding domain.
Cellular localization
Nucleus. Chromosome > telomere.
Target information above from: UniProt accessionQ9H668
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- AAF 44 antibody
- AAF44 antibody
- RPA 32 antibody
see all
Database links
- Entrez Gene: 79991 Human
- Omim: 613128 Human
- SwissProt: Q9H668 Human
- Unigene: 62314 Human
Anti-OBFC1 antibody images:
Western blot - OBFC1 antibody (ab57764)
OBFC1 antibody (ab57764) at 1ug/lane + Jurkat cell lysate at 25ug/lane.
References for Anti-OBFC1 antibody (ab57764)
ab57764 has not yet been referenced specifically in any publications.
Publishing research using ab57764? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"