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Products:Cancer >> Tumor biomarkers >> Other

Anti-OLFM4 antibody (ab55937)

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Overview

Product name

Anti-OLFM4 antibody
See all OLFM4 products (5) ...

Description

Rabbit polyclonal to OLFM4

Tested applications

WB, ELISAmore details

Cross reactivity

Reacts with

Recombinant Fragment

Predicted to work with

Human

Immunogen

Synthetic peptide corresponding to N-terminal residues of human OLFM4

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: 0.01% Sodium Azide
Constituents: 50% Glycerol, PBS

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Clonality

Polyclonal

Isotype

IgG

Research areas

Cancer >> Tumor biomarkers >> Other

Applications

Show applications key

Our Abpromise guarantee covers the use of ab55937 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

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    WB

     WB: Use a concentration ...Read more →

    WB: Use a concentration of 1 µg/mlPredicted molecular weight: 57 kDa.(This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.)

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    ELISA

     ELISA: Use at an assay d...Read more →

    ELISA: Use at an assay dependent dilution.

Target

Function

An antiapoptotic factor that promotes tumor growth. Promotes proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. Facilitates cell adhesion.

Tissue specificity

Expressed during myeloid lineage development. Strongly expressed in the prostate, small intestine and colon and moderately expressed in the bone marrow and stomach. Highly expressed in pancreatic cancer tissues and shows an elevated expression level during the early S phase of the cell cycle. Also expressed at high levels in stomach cancer and colon cancer tissues.

Sequence similarities

Contains 1 olfactomedin-like domain.

Domain

The olfactomedin-like domain is involved in the interaction with cadherin.

Post-translational
modifications

N-glycosylated.

Cellular localization

Secreted > extracellular space. According to PubMed:15059901, found in mitochondrion and nucleus.

Target information above from: UniProt accessionQ6UX06 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • Antiapoptotic protein GW112 antibody
  • bA209J19.1 antibody
  • G-CSF-stimulated clone 1 protein antibody
  • GC1 antibody
  • GW112 antibody
  • hGC 1 antibody
  • hGC-1 antibody
  • hOLfD antibody
  • KIAA4294 antibody
  • olfactomedin 4 antibody
  • Olfactomedin-4 antibody
  • OlfD antibody
  • OLFM4 antibody
  • OLFM4_HUMAN antibody
  • OLM4 antibody
  • UNQ362 antibody
see all

References for Anti-OLFM4 antibody (ab55937)

ab55937 has not yet been referenced specifically in any publications.

Publishing research using ab55937? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"