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Products:Neuroscience >> Cell Type Marker >> Glia marker >> Oligodendrocyte marker
This fast track antibody is not yet fully characterised. It is subject to these terms and conditions
Overview
Product name
Anti-OLIG1 antibody
See all Olig1 products (10) ...
Description
Goat polyclonal to OLIG1
This product is a fast track antibody. It has been affinity purified and shows high titre values against the immunizing peptide by ELISA. Read the terms of use »
Cross reactivity
Predicted to work with
Mouse, Rat, Human
Immunogen
Synthetic peptide: (C)SLGLAAVQAQFSK, corresponding to C terminal amino acids 259-271 of Human OLIG1
(C)SLGLAAV QAQFSK
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, 5mg/ml Tris, pH 7.3
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Purification notes
This antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Clonality
Polyclonal
Isotype
IgG
Research areas
Neuroscience >> Neurology process >> Neurogenesis
Neuroscience >> Cell Type Marker >> Glia marker >> Oligodendrocyte marker
Applications
Application notes
This antibody gave a positive result in ELISA against the immunizing peptide.
Antibody detection limit dilution 1:8,000.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Promotes formation and maturation of oligodendrocytes, especially within the brain. Cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube.
Tissue specificity
Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas is highly variable.
Sequence similarities
Contains 1 basic helix-loop-helix (bHLH) domain.
Cellular localization
Nucleus.
Target information above from: UniProt accessionQ8TAK6
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Basic domain helix loop helix protein class B 6 antibody
- Basic domain helix loop helix protein class B6 antibody
- BHLH B6 antibody
see all
Database links
- Entrez Gene: 116448 Human
- Entrez Gene: 50914 Mouse
- Entrez Gene: 60394 Rat
- Omim: 606385 Human
- SwissProt: Q8TAK6 Human
- SwissProt: Q9JKN5 Mouse
- SwissProt: Q9WUQ3 Rat
- Unigene: 56663 Human
see all
References for Anti-OLIG1 antibody (ab28748)
ab28748 has not yet been referenced specifically in any publications.
Publishing research using ab28748? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"