Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Reassurance, Refunds & Replacements
If your product does not perform as described on this datasheet, we will refund or replace your product...
Read our guarantee »Overview
Product name
Okadaic acid
Description
PP1 and PP2A inhibitor
Biological description
Potent inhibitor of protein phosphatase 1 (IC50 = 3 - 15 nM) and protein phosphatase 2A (IC50 = 0.1-1 nM). Highly selective over PP2B, PP2C and a range of other phosphatases. Tumor promotor.
Purity
> 98%
General notes
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Properties
Chemical name
9,10-Deepithio-9,10-didehydroacanthifolicin
Molecular Weight
805.01
Chemical structure
Molecular formula
C44H68O13
CAS Number
78111-17-8
Solubility
Soluble in DMSO to 100 mM
Storage instructions
Store at -20°C (desiccating conditions).
Research areas
Biochemicals >> Pharmacology >> Enzymes >> Phosphatase >> PP1 & PP2A >> Inhibitors
Biochemicals >> Chemical Type >> Biochemicals
References for Okadaic acid (ab120375)
This product has been referenced in:
- Fernández JJ et al. Okadaic acid, useful tool for studying cellular processes. Curr Med Chem 9:229-62 (2002).Read more (PubMed: 11860357) »
- Cohen P et al. Okadaic acid: a new probe for the study of cellular regulation. Trends Biochem Sci 15:98-102 (1990).Read more (PubMed: 2158158) »
See all 3 publications for this product
Publishing research using ab120375? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"