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Products:Neuroscience >> Cell Type Marker >> Glia marker >> Oligodendrocyte marker
Overview
Product name
Anti-Olig1 antibody
See all Olig1 products (10) ...
Description
Mouse monoclonal to Olig1
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Recombinant full length protein: PDAKEEQQQQ LRRKINSRER KRMQDLNLAM DALREVILPY SAAHCQGAPG RKLSKIATLL LARNYILLLG SSLQELRRAL , corresponding to amino acids 80-159 of Human Olig1
PDAKEEQQQQ LRRKINSRER KRMQDLNLAM DALREVILPY SAAHCQGAPG RKLSKIATLL LARNYILLLG SSLQELRRAL
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG2a
Light chain type
kappa
Research areas
Neuroscience >> Neurology process >> Neurogenesis
Neuroscience >> Cell Type Marker >> Glia marker >> Oligodendrocyte marker
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Western blot - Olig1 antibody (ab57987)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab57987 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: Use at a concentration of 1-5 µg/ml.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Promotes formation and maturation of oligodendrocytes, especially within the brain. Cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube.
Tissue specificity
Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas is highly variable.
Sequence similarities
Contains 1 basic helix-loop-helix (bHLH) domain.
Cellular localization
Nucleus.
Target information above from: UniProt accessionQ8TAK6
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Basic domain helix loop helix protein class B 6 antibody
- Basic domain helix loop helix protein class B6 antibody
- BHLH B6 antibody
see all
Database links
- Entrez Gene: 116448 Human
- Omim: 606385 Human
- SwissProt: Q8TAK6 Human
- Unigene: 56663 Human
Anti-Olig1 antibody images:
Western blot - Olig1 antibody (ab57987)
Western blot against tagged recombinant protein immunogen using ab57987 Olig1 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa
References for Anti-Olig1 antibody (ab57987)
ab57987 has not yet been referenced specifically in any publications.
Publishing research using ab57987? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"