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Products:Neuroscience >> Cell Type Marker >> Glia marker >> Oligodendrocyte marker
Overview
Product name
Anti-Olig1 antibody
See all Olig1 products (10) ...
Description
Rabbit polyclonal to Olig1
Tested applications
IHC-Frmore details
Cross reactivity
Reacts with
Rat
Predicted to work with
Mouse, Human, Pig, Chimpanzee, Monkey, Baboon, Marmoset (common)
Immunogen
Synthetic peptide: SARPDAKEEQQQQLR-C, corresponding to amino acids 93-107 of Human Olig1
SARPDAKEEQ QQQLR-C
Positive control
White matter of adult rat spinal cord.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.5% Sodium Azide
Constituents: PBS, Whole serum
Purity
Whole antiserum
Clonality
Polyclonal
Isotype
IgG
Research areas
Neuroscience >> Neurology process >> Neurogenesis
Neuroscience >> Cell Type Marker >> Glia marker >> Oligodendrocyte marker
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Immunohistochemistry (Frozen sections) - Olig1 antibody (ab68105)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab68105 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-Fr: 1/100 - 1/600.
Target
Function
Promotes formation and maturation of oligodendrocytes, especially within the brain. Cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube.
Tissue specificity
Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas is highly variable.
Sequence similarities
Contains 1 basic helix-loop-helix (bHLH) domain.
Cellular localization
Nucleus.
Target information above from: UniProt accessionQ8TAK6
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Basic domain helix loop helix protein class B 6 antibody
- Basic domain helix loop helix protein class B6 antibody
- BHLH B6 antibody
see all
Database links
- Entrez Gene: 116448 Human
- Entrez Gene: 50914 Mouse
- Entrez Gene: 60394 Rat
- Omim: 606385 Human
- SwissProt: Q8TAK6 Human
- SwissProt: Q9JKN5 Mouse
- SwissProt: Q9WUQ3 Rat
- Unigene: 56663 Human
see all
Anti-Olig1 antibody images:
Immunohistochemistry (Frozen sections) - Olig1 antibody (ab68105)
ab68105, at 1/100 dilution, staining Olig1 in the white matter of adult rat spinal cord by Immunohistochemistry on cryo-preserved sections, using anti-rabbit Cy3-conjugated secondary antibodies (red) and DAPI (blue) as a nuclear counterstain.
References for Anti-Olig1 antibody (ab68105)
ab68105 has not yet been referenced specifically in any publications.
Publishing research using ab68105? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"