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Anti-ORC2 antibody [3G6] (ab22537)

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Overview

Product name

Anti-ORC2 antibody [3G6]
See all ORC2 products (7) ...

Description

Rat monoclonal [3G6] to ORC2

Specificity

ab22537 recognises ORC2

Tested applications

WB, IPmore details

Cross reactivity

Reacts with

Human

Immunogen

Full length protein (Human): ORC2 (hsORC)

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 0.1% Sodium Azide
Constituents: PBS

Concentration

Concentration information loading...

Purity

Protein G purified

Clonality

Monoclonal

Clone number

3G6

Myeloma

x63-Ag8.653

Isotype

IgG2a

Research areas

Epigenetics and Nuclear Signaling >> Nuclear Signaling Pathways >> Nuclear Receptors >> Nuclear Pore Complex
Epigenetics and Nuclear Signaling >> DNA / RNA >> DNA Synthesis >> Other

Applications

Show applications key

Our Abpromise guarantee covers the use of ab22537 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Function

Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.

Sequence similarities

Belongs to the ORC2 family.

Cellular localization

Nucleus.

Target information above from: UniProt accessionQ13416 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • orc2 antibody
  • ORC2_HUMAN antibody
  • ORC2L antibody
  • Origin of replication 2 (yeast homolog) like antibody
  • Origin recognition complex subunit 2 antibody
  • Origin recognition complex subunit 2 isoform B antibody
  • Origin recognition complex subunit 2 like (yeast) antibody
  • Origin recognition complex, subunit 2, S. cerevisiae, homolog of antibody
  • Origin recognition complex, subunit 2-like (S. cerevisiae) antibody
see all

Database links

References for Anti-ORC2 antibody [3G6] (ab22537)

This product has been referenced in:

  • Song Wet al. A conserved physical and functional interaction between the cell cycle checkpoint clamp loader and DNA ligase I of eukaryotes. J Biol Chem 282:22721-30 (2007). WB; Human.Read more (PubMed: 17561505) »

See 1 publication for this product

Publishing research using ab22537? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"