Otx2 antibody (ab76748)

Product Name 

Otx2 antibody

Product type 

Primary antibodies

Description 

Rabbit polyclonal to Otx2

Immunogen 

Synthetic peptide derived from the N terminal domain of human Otx2

Reacts with 

Hu

Predicted to react 
(species key)

Rat
(Due to sequence homology)

Specificity 

Reacts specifically with 31 kDa Otx2 protein.

Tested applications 
(see key)

IHC-P, WB

Abreviews 

Customer reviews (see key)

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Application notes 
(see key)

Recommended dilutions
IHC-P: 1/50 - 1/200.
WB: 1/100 - 1/1000. Predicted molecular weight: 32 kDa.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Nuclear

Research areas 

Developmental Biology >> Organogenesis >> Nervous system development
Developmental Biology >> Lineage specification >> Ectoderm
Developmental Biology >> Embryogenesis >> Axis formation and symmetry
Stem Cells >> Lineage Markers >> Ectoderm
Chromatin and Nuclear Signaling >> Transcription >> Other factors
Neuroscience >> Sensory System >> Visual system

Relevance 

Homeobox protein Otx2 is a member of the bicoid sub-family of homeodomain-containing transcription factors. It is an early marker of endodermal differentiation of embryonic stem cells and may play a role in the development of the brain and the sense organs. Two distinct isoforms have been identified.
Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.

Database links 

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Whole antiserum

Storage buffer 

Preservative: None
Constituents: Whole serum

Form 

Liquid

Concentration 

Concentration not determined - why is this?

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

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