Anti-P Glycoprotein antibody [UIC2] (Phycoerythrin) (ab93590)


  • Product name
    Anti-P Glycoprotein antibody [UIC2] (Phycoerythrin)
    See all P Glycoprotein primary antibodies
  • Description
    Mouse monoclonal [UIC2] to P Glycoprotein (Phycoerythrin)
  • Host species
  • Conjugation
    Phycoerythrin. Ex: 488nm, Em: 575nm
  • Tested applications
    Suitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Mouse Balb/c 3T3 fibroblasts transfected with Human P Glycoprotein cDNA

  • Positive control
    • 8226 DOX40 and 8226/S cell lines
  • General notes

    ab93590 has been reported to inhibit MDR1-mediated efflux.



Our Abpromise guarantee covers the use of ab93590 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 5µl for 106 cells.

Use 5 µl/test for 105-8 cells in 100µl.





ab91363 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.



  • Function
    Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
  • Tissue specificity
    Expressed in liver, kidney, small intestine and brain.
  • Involvement in disease
    Genetic variations in ABCB1 are associated with susceptibility to inflammatory bowel disease type 13 (IBD13) [MIM:612244]. Inflammatory bowel disease is characterized by a chronic relapsing intestinal inflammation. It is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints. Crohn disease and ulcerative colitis are commonly classified as autoimmune diseases.
  • Sequence similarities
    Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
    Contains 2 ABC transmembrane type-1 domains.
    Contains 2 ABC transporter domains.
  • Cellular localization
  • Information by UniProt
  • Database links
  • Alternative names
    • ABC20 antibody
    • ABCB1 antibody
    • ATP binding cassette, sub family B (MDR/TAP), member 1 antibody
    • ATP-binding cassette sub-family B member 1 antibody
    • CD243 antibody
    • CLCS antibody
    • Colchicin sensitivity antibody
    • Doxorubicin resistance antibody
    • GP170 antibody
    • MDR1 antibody
    • MDR1_HUMAN antibody
    • Multidrug resistance 1 antibody
    • Multidrug resistance protein 1 antibody
    • P glycoprotein 1 antibody
    • P gp antibody
    • P-glycoprotein 1 antibody
    • PGY1 antibody
    see all


  • Staining of the 8226/S (blue histogram) and 8226 DOX40 (purple histogram) cell lines with PE Mouse IgG2a, K Isotype Control (left) or ab93590 (right). Total viable cells were used for analysis.


This product has been referenced in:
  • Wang CW  et al. 7-ketocholesterol and 27-hydroxycholesterol decreased doxorubicin sensitivity in breast cancer cells: estrogenic activity and mTOR pathway. Oncotarget 8:66033-66050 (2017). Read more (PubMed: 29029490) »
  • Huang XC  et al. Parguerenes: Marine red alga bromoditerpenes as inhibitors of P-glycoprotein (ABCB1) in multidrug resistant human cancer cells. Biochem Pharmacol 85:1257-68 (2013). Read more (PubMed: 23415901) »

See all 4 Publications for this product

Customer reviews and Q&As

Thank you for contacting us.

Please buy ab91363.

I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

Thank you for your inquiry.

I am happy to confirm that ab93590 (the isotype control for it (ab1282) will not bind anything specifically, but mark the background staining) is suitable for flow cytometry. It will recognise P-glycoprotein 1 (Pgp...

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Thank you for your enquiry and your interest.

I can confirm that ab93590has been testedin Flow cytometry and ab1282 can be used as isotype control.

We also have other primary antibodies against P Glycoprotein, here are some non-conj...

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Merci pour votre enquête ainsi que pour votre patience pendant que je contactais le laboratoire. Le laboratoire m'a pu répondre que la concentration de cet anticorps est d'environ 0.5ug par 5ul. Donc ceci fait 0.1mg/ml. Le laboratoire à testé 5ul de ce...

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