Anti-P Glycoprotein antibody (ab98322)
- Product nameAnti-P Glycoprotein antibodySee all P Glycoprotein primary antibodies ...
- DescriptionRabbit polyclonal to P Glycoprotein
- Tested applicationsWB more details
- Species reactivityReacts with: Human
Synthetic peptide corresponding to a region within internal sequence amino acids 863-912 of Human P Glycoprotein (NP_000918).
- Positive control
- NCI-H226 cell lysate
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
- Storage bufferPreservative: None
Constituents: 2% Sucrose, PBS
- Concentration information loading...
- PurityImmunogen affinity purified
- Clonality Polyclonal
- Research Areas
Our Abpromise guarantee covers the use of ab98322 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||WB: Use a concentration of 1 µg/ml. Predicted molecular weight: 141 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.|
- FunctionEnergy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
- Tissue specificityExpressed in liver, kidney, small intestine and brain.
- Involvement in diseaseGenetic variations in ABCB1 are associated with susceptibility to inflammatory bowel disease type 13 (IBD13) [MIM:612244]. Inflammatory bowel disease is characterized by a chronic relapsing intestinal inflammation. It is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints. Crohn disease and ulcerative colitis are commonly classified as autoimmune diseases.
- Sequence similaritiesBelongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
Contains 2 ABC transmembrane type-1 domains.
Contains 2 ABC transporter domains.
- Cellular localizationMembrane.
- ABC20 antibody
- ABCB1 antibody
- ATP binding cassette, sub family B (MDR/TAP), member 1 antibody
- ATP-binding cassette sub-family B member 1 antibody
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- Doxorubicin resistance antibody
- GP170 antibody
- MDR1 antibody
- MDR1_HUMAN antibody
- Multidrug resistance 1 antibody
- Multidrug resistance protein 1 antibody
- P glycoprotein 1 antibody
- P gp antibody
- P-glycoprotein 1 antibody
- PGY1 antibody
Anti-P Glycoprotein antibody images
Anti-P Glycoprotein antibody (ab98322) at 1 µg/ml (in 5% skim milk / PBS buffer) + NCI-H226 cell lysate at 10 µg
Predicted band size : 141 kDa
ab98322 staining P Glycoprotein in placental tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
ab98322 staining P Glycoprotein in adrenal tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
References for Anti-P Glycoprotein antibody (ab98322)
ab98322 has not yet been referenced specifically in any publications.