Anti-P2Y1 antibody (ab168918)
Key features and details
- Mouse polyclonal to P2Y1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-P2Y1 antibody
See all P2Y1 primary antibodies -
Description
Mouse polyclonal to P2Y1 -
Host species
Mouse -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Guinea pig, Cow -
Immunogen
Recombinant full length protein within Human P2Y1 aa 1-400. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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Positive control
- P2Y1 transfected 293T cell lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
pH: 7.4
Constituent: 99% PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab168918 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 42 kDa.
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Notes |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 42 kDa. |
Target
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Function
Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 281963 Cow
- Entrez Gene: 100135592 Guinea pig
- Entrez Gene: 5028 Human
- Entrez Gene: 18441 Mouse
- Entrez Gene: 25265 Rat
- Omim: 601167 Human
- SwissProt: P48042 Cow
- SwissProt: P59902 Guinea pig
see all -
Alternative names
- ATP receptor antibody
- P2 purinoceptor subtype Y1 antibody
- P2RY1 antibody
see all
Images
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All lanes : Anti-P2Y1 antibody (ab168918) at 1 µg/ml
Lane 1 : P2Y1 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 15 µl per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution
Developed using the ECL technique.
Predicted band size: 42 kDa
Datasheets and documents
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Datasheet download
References (2)
ab168918 has been referenced in 2 publications.
- Milior G et al. Distinct P2Y Receptors Mediate Extension and Retraction of Microglial Processes in Epileptic and Peritumoral Human Tissue. J Neurosci 40:1373-1388 (2020). PubMed: 31896671
- Cabou C et al. Pharmacological inhibition of the F1 -ATPase/P2Y1 pathway suppresses the effect of apolipoprotein A1 on endothelial nitric oxide synthesis and vasorelaxation. Acta Physiol (Oxf) 226:e13268 (2019). PubMed: 30821416