Anti-P2Y11 antibody - Extracellular domain (ab140878)
Key features and details
- Rabbit polyclonal to P2Y11 - Extracellular domain
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-P2Y11 antibody - Extracellular domain
See all P2Y11 primary antibodies -
Description
Rabbit polyclonal to P2Y11 - Extracellular domain -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Monkey, Gorilla -
Immunogen
A 16 amino acid synthetic peptide from the 3rd extracellular domain of the Human P2Y11 protein (NP_002557.2).
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Positive control
- Human dendritic cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. -
Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab140878 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use a concentration of 8 - 16 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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Notes |
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IHC-P
Use a concentration of 8 - 16 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
Target
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Function
Receptor for ATP and ADP coupled to G-proteins that activate both phosphatidylinositol-calcium and adenylyl cyclase second messenger systems. Not activated by UTP or UDP. -
Tissue specificity
Highest expression in liver and spleen. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 109023065 Gorilla
- Entrez Gene: 5032 Human
- Omim: 602697 Human
- SwissProt: Q96G91 Human
- Unigene: 14468 Human
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Alternative names
- P2RY11 antibody
- P2Y purinoceptor 11 antibody
- P2Y11 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab140878 has been referenced in 1 publication.
- Dreisig K et al. Human P2Y11 Expression Level Affects Human P2X7 Receptor-Mediated Cell Death. Front Immunol 9:1159 (2018). PubMed: 29937766