Anti-P2Y2 antibody (ab168535)
Key features and details
- Mouse polyclonal to P2Y2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-P2Y2 antibody
See all P2Y2 primary antibodies -
Description
Mouse polyclonal to P2Y2 -
Host species
Mouse -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow, Pig, Rhesus monkey -
Immunogen
Recombinant full length protein within Human P2Y2 aa 1-400. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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Positive control
- P2Y2 transfected 293T cell lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
pH: 7.4
Constituent: 99% PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab168535 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 42 kDa.
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Notes |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 42 kDa. |
Target
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Function
Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP = ATP > ATP-gamma-S >> 2-methylthio-ATP = ADP. -
Tissue specificity
Spleen, testis, kidney, liver, lung, heart and brain. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 282638 Cow
- Entrez Gene: 5029 Human
- Entrez Gene: 18442 Mouse
- Entrez Gene: 450248 Pig
- Entrez Gene: 29597 Rat
- Entrez Gene: 718603 Rhesus monkey
- Omim: 600041 Human
- SwissProt: O18951 Cow
see all -
Alternative names
- ATP receptor antibody
- HP2U antibody
- Human P2U nucleotide receptor mRNA complete cds antibody
see all
Images
Datasheets and documents
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Datasheet download
References (1)
ab168535 has been referenced in 1 publication.
- Flores-Muñoz C et al. Restraint of Human Skin Fibroblast Motility, Migration, and Cell Surface Actin Dynamics, by Pannexin 1 and P2X7 Receptor Signaling. Int J Mol Sci 22:N/A (2021). PubMed: 33499026