Anti-P2Y6 antibody (ab198805)
Key features and details
- Rabbit polyclonal to P2Y6
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-P2Y6 antibody -
Description
Rabbit polyclonal to P2Y6 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Rat -
Immunogen
Synthetic peptide corresponding to Human P2Y6 (internal sequence).
Database link: Q15077 -
Positive control
- Human brain malignant glioma tissue lysate and Human lung cancer tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab198805 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/50 - 1/200.
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WB |
1/500 - 1/2000. Predicted molecular weight: 36 kDa.
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Notes |
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IHC-P
1/50 - 1/200. |
WB
1/500 - 1/2000. Predicted molecular weight: 36 kDa. |
Target
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Function
Receptor for extracellular UDP > UTP > ATP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 5031 Human
- Entrez Gene: 117264 Rat
- Omim: 602451 Human
- SwissProt: Q15077 Human
- SwissProt: Q63371 Rat
- Unigene: 16362 Human
- Unigene: 10671 Rat
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Alternative names
- G coupled nucleotide receptor antibody
- G protein coupled 6 antibody
- MGC15335 antibody
see all
Images
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Anti-P2Y6 antibody (ab198805) at 1/550 dilution + Human brain malignant glioma tissue lysate at 40 µg
Developed using the ECL technique.
Predicted band size: 36 kDa
Exposure time: 1 minuteGel: 10% SDS-PAGE
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Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue labeling P2Y6 with ab198805 at 1/40 dilution.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab198805 has been referenced in 1 publication.
- Wang H et al. Uridine Diphosphate Promotes Rheumatoid Arthritis Through P2Y6 Activation. Front Pharmacol 12:658511 (2021). PubMed: 33953685