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Product Name 

P4HA2 antibody

 

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Product type 

Primary antibodies

Description 

Rabbit polyclonal to P4HA2

Immunogen 

Synthetic peptide corresponding to a region between residues 150 and 200 of Human P4HA2 (NP_004190.1)

Reacts with 
(species key)

Hu

Tested applications 
(see key)

IP


Abreviews 

Customer reviews
(see key)


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Application notes 
(see key)

Recommended dilutions
IP: Use at 2-5µg/mg of lysate.


Is unsuitable for WB.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

Whole cell lysate from HeLa cells.

Cellular localization 

Endoplasmic reticulum lumen.

Research areas 

Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Proteins >> Collagen
Signal Transduction >> Metabolism >> Amino Acids

Relevance 

P4HA2 is a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. P4HA2 catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.

 

Alternative names P4HA2 antibody (ab70811)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

8974    (Human)

Omim

    

600608    (Human)

SwissProt

    

O15460    (Human)

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Immunogen affinity purified

Storage buffer 

Preservative: 0.09% Sodium Azide
Constituents: PBS, 8mM Phosphate, 60mM Citrate, 150mM Tris, pH 7-8

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Store at +4°C.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this P4HA2 antibody is on this datasheet. But please do contact us if you would like any reassurance!


 

Search PubMed (MEDLINE) for references to P4HA2

 

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Positive Controls for P4HA2 antibody

ab29545

  

HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate

 

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