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Overview

  • Product nameAnti-PABPC3 antibodySee all PABPC3 primary antibodies ...
  • Description
    Rabbit polyclonal to PABPC3
  • Tested applicationsWB, IHC-P more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 411-609 of Human PABPC3 (Q9H361).

  • Positive controlJurkat, Raji and K562 whole cell lysates; Human hepatoma tissue.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferpH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 0.75% Glycine, 1.21% Tris, 20% Glycerol
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Clonality Polyclonal
  • IsotypeIgG
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab126178 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB WB: 1/500 - 1/3000. Predicted molecular weight: 70 kDa.
IHC-P IHC-P: 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionBinds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Binds poly(A) with a slightly lower affinity as compared to PABPC1.
  • Tissue specificityTestis specific.
  • Sequence similaritiesBelongs to the polyadenylate-binding protein type-1 family.
    Contains 1 PABC domain.
    Contains 4 RRM (RNA recognition motif) domains.
  • Cellular localizationCytoplasm.

    • Target information above from: UniProt accession Q9H361 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
    • Alternative names
        PABP-3 antibodyPABP3 antibodyPABP3_HUMAN antibody
        PABPC3 antibodyPABPL3 antibodyPoly(A) binding protein 3 antibodyPoly(A)-binding protein 3 antibodyPolyadenylate binding protein 3 antibodyPolyadenylate-binding protein 3 antibodyRP11-165I9.5 antibodyTestis specific poly(A) binding protein antibodyTestis-specific poly(A)-binding protein antibodytPABP antibody
      see all

    Anti-PABPC3 antibody images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PABPC3 antibody (ab126178)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PABPC3 antibody (ab126178)
      ab126178, at 1/500 dilution, staining PABPC3 in paraffin-embedded Hepatoma tissue by Immunohistochemistry.

    References for Anti-PABPC3 antibody (ab126178)

    ab126178 has not yet been referenced specifically in any publications.

    Publishing research using ab126178 ? Please let us know so that we can cite the reference in this datasheet

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"