PAC-1, caspase-3 activator (ab142074)
Key features and details
- Potent caspase-3 activator
- CAS Number: 315183-21-2
- Purity: > 95%
- Soluble in water to 5 mM and in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
PAC-1, caspase-3 activator -
Description
Potent caspase-3 activator -
Purity
> 95% -
General notes
This product is manufactured by BioVision, an Abcam company and was previously called 1654 PAC-1. 1654-10 is the same size as the 10 mg size of ab142074.
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CAS Number
315183-21-2 -
Chemical structure
Properties
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Chemical name
2-(4-Benzylpiperazin-1-yl)-N'-[(Z)-(6-oxo-5-prop-2-enylcyclohexa-2,4-dien-1-ylidene)methyl]acetohydrazide -
Molecular weight
392.49 -
Molecular formula
C23H28N4O2 -
PubChem identifier
6851947 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 5 mM and in DMSO to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C=CCC1=CC=CC(=CNNC(=O)CN2CCN(CC2)CC3=CC=CC=C3)C1=O -
Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab142074 has been referenced in 1 publication.
- Dick SA et al. Caspase 3 cleavage of Pax7 inhibits self-renewal of satellite cells. Proc Natl Acad Sci U S A 112:E5246-52 (2015). PubMed: 26372956