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Product Name
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PACS1 antibody
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to PACS1
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Immunogen
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Synthetic peptide corresponding to C terminal residues of human PACS1 (Phosphofurin acidic cluster sorting protein 1)
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Reacts with
(species key)
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Hu, Ms, Rat
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Tested applications
(see key)
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ELISA, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: Use at an assay dependent dilution.
WB: Use at a concentration of 1 µg/ml for 2hrs. Predicted molecular weight: 105 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Golgi apparatus, trans Golgi network.
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Research areas
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Signal Transduction >> Protein Trafficking >> Golgi Proteins
Signal Transduction >> Protein Trafficking >> Vesicle Transport >> Coat Proteins
Microbiology >> Interspecies Interaction >> Host Virus Interaction
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Relevance
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PACS1 is a coat protein that is involved in the localization of trans Golgi network (TGN) membrane proteins that contain acidic cluster sorting motifs. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. PACS1 is known to interact with HIV-1 Nef, AP-1 and AP-3 but not with AP-2.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.01% Sodium Azide
Constituents: 50% Glycerol, PBS Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Sodium Azide MSDS
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Purification notes
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Purified by antigen specific affinity chromatography.
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Form
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Liquid
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Concentration
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0.500 mg/ml
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this PACS1 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to PACS1
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PACS1 antibody - more information
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Customer reviews (feedback) regarding PACS1 antibody |
Customer FAQs regarding PACS1 antibody |
Protocols for PACS1 antibody |
Price and availability of products related to PACS1 antibody |
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PACS1 antibody - related products:
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PACS1 antibody - other tools:
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Contact Abcam with a Technical Enquiry about PACS1 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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