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Western blot - PADI1 / PAD1 antibody (ab24008)
Western blot - PADI1 / PAD1 antibody (ab24008)
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Product Name 

PADI1 / PAD1 antibody

Product type 

Primary antibodies

Description 

Rabbit polyclonal to PADI1 / PAD1

Immunogen 

A 15 residue synthetic peptide derived from a domain specific for Human peptidylarginine deiminase type 1 protein.

Reacts with 
(species key)

Hu

Specificity 

Reactivity with other PAD isoforms has not yet been determined.

Tested applications 
(see key)

WB


Abreviews 

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Application notes 
(see key)

Recommended dilutions
WB: 1/200 - 1/1000. Predicted molecular weight: 75 kDa.

Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Cytoplasmic and Nuclear

Research areas 

Chromatin and Nuclear Signaling >> Chromatin Modifying Enzymes >> Methylation >> Arginine Deimination
Chromatin and Nuclear Signaling >> Chromatin Modifying Enzymes >> Arginine Deiminases
Signal Transduction >> Metabolism >> Amino Acids

Relevance 

Peptidylarginine deiminases (PADs) convert arginine residues in proteins into citrullines. They are suspected to be involved in multiple sclerosis and rheumatoid arthritis pathophysiology, and they play a role in epidermis homeostasis and possibly in regulation of gene expression through histone modification. In humans, five isoforms encoded by the genes PADI1-4, 6 are known so far.

 

PADI1 / PAD1 antibody (ab24008)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

29943    (Human)

Omim

    

607934    (Human)

SwissProt

    

Q9ULC6    (Human)

Unigene

    

412941    (Human)

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Whole antiserum

Storage buffer 

Preservative: None
Constituents: Whole serum

Form 

Liquid

Concentration 

Concentration not determined - why is this?

Storage instructions 

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this PADI1 / PAD1 antibody is on this datasheet. But please do contact us if you would like any reassurance!


See below for PADI1 / PAD1 antibody images, references, products related to ab24008 and other tools.

 

PADI1 / PAD1 antibody images:

Product image  Western blot - PADI1 / PAD1 antibody (ab24008)

Western blot - PADI1 / PAD1 antibody (ab24008)

PADI1 / PAD1 antibody (ab24008) + Human epidermis

Predicted band size : 75 kDa
Observed band size : 70 kDa (why is the actual band size different from the predicted?)

 
 

Search PubMed (MEDLINE) for references to PADI1 / PAD1

 

PADI1 / PAD1 antibody - more information

Customer reviews (feedback) regarding PADI1 / PAD1 antibody

Customer FAQs regarding PADI1 / PAD1 antibody

Protocols for PADI1 / PAD1 antibody

Price and availability of products related to PADI1 / PAD1 antibody

 

PADI1 / PAD1 antibody - related products:

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PADI1 / PAD1 antibody - other tools:

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