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Products:Cardiovascular >> Blood >> Platelets
Overview
Product name
PAFAH1B2 protein (His tag)
Protein description
Recombinant full length protein (Human), His tag at N terminus.
Expression host
E. coli
Properties
Purity
>95% by SDS-PAGE
Form
Liquid
Storage instructions
Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 0.05% Tween 20, 10mM Tris, pH 8.0
Concentration
Concentration information loading...
Research areas
Signal Transduction >> Metabolism >> Lipid metabolism
Cardiovascular >> Lipids / Lipoproteins >> Lipid Metabolism >> Hydrolysis
Cardiovascular >> Blood >> Platelets
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SDS-PAGE - PAFAH1B2 protein (ab40601)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab40601 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
SDS-PAGE: Use at an assay dependent dilution.
MS: Use at an assay dependent dilution.
Application notes
This peptide can be used with studies using ab15875.
Protein info
Relevance
Platelet-activating factor (PAF) is a biologically active phospholipid with diverse biologic effects. PAF is degraded to inactive products by hydrolysis of the acetyl group at the sn2 position to produce the biologically inactive products LYSO PAF and acetate. This reaction is catalyzed by PAF acetylhydrolase (PAFAH). The various monomeric and multimeric forms of the enzyme are composed of alpha, beta, and gamma PAFAH subunits. The catalytic activity of the enzyme resides in the beta and gamma subunits, whereas the alpha subunit has regulatory activity. Trimer formation is not essential for the catalytic activity.
Cellular localization
Cytoplasmic
PAFAH1B2 protein (His tag) images:
SDS-PAGE - PAFAH1B2 protein (ab40601)
Analysis of PAFAH1B2 Recombinant protein. 4-20% SDS gradient gel. Coomassie blue staining. Band size approximately 25 kDa.
References for PAFAH1B2 protein (His tag) (ab40601)
ab40601 has not yet been referenced specifically in any publications.
Publishing research using ab40601? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"