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Product Name
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PAI1 antibody [3E529]
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See all PAI1 / Serpine 1 antibodies (20)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [3E529] to PAI1
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Immunogen
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Recombinant full length protein: human PAI.
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Reacts with
(species key)
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Hu
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Specificity
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PAI1 antibody [3E529] (ab20286) recognizes both free and complexed forms of Human PAI1.
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Tested applications
(see key)
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ELISA
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: Use at an assay dependent dilution.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Secreted
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Research areas
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Cancer >> Tumor biomarkers >> Other
Cell Biology >> Proteolysis / Ubiquitin >> Protease inhibitors >> Serine protease inhibitors >> SERPINs
Cardiovascular >> Blood >> Fibrinolysis / Thrombolysis
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Relevance
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PAI1 (plasminogen activator inhibitor 1) is originally cloned from human endothelial cell (Pannekoek 1986, Ginsburg 1986) and rat hepatoma cell 3 cDNA libraries. As a member of the serpin family of serine protease inhibitors, PAI1 inhibits both tissue type palsminogen activator (tPA) and urokinase type plasminogen activator (uPA). High PAI1 levels are associated with an increased risk of thromboembolic disease while PAI1 deficiency may represent an inherited autosomal recessive bleeding disorder.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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3E529
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Isotype
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IgG
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Purity
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Protein A purified
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Storage buffer
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Preservative: None
Constituents: 50mM Sodium phosphate, 100mM Sodium chloride, 1mM EDTA. pH 6.6 Material safety datasheet (MSDS) for this product:
Sodium Phosphate MSDS
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Purification notes
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PAI1 antibody [3E529] (ab20286) is >98% pure (SDS-PAGE).
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Store at +4°C.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this PAI1 antibody [3E529] is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to PAI1
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PAI1 antibody [3E529] - more information
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Customer reviews (feedback) regarding PAI1 antibody [3E529] |
Customer FAQs regarding PAI1 antibody [3E529] |
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PAI1 antibody [3E529] - related products:
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PAI1 antibody [3E529] - other tools:
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