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Products:Epigenetics and Nuclear Signaling >> DNA / RNA >> DNA / Nucleotides
Overview
Product name
Anti-PAICS antibody
See all PAICS products (2) ...
Description
Rabbit polyclonal to PAICS
Tested applications
Cross reactivity
Reacts with
Human
Predicted to work with
Mouse, Rat, Chicken, Cow
Immunogen
synthetic peptide corresponding to a region of Human PAICS
Positive control
Fetal brain lysate
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 2% Sucrose, PBS
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Signal Transduction >> Metabolism >> Energy Metabolism
Epigenetics and Nuclear Signaling >> DNA / RNA >> DNA / Nucleotides
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Western blot - PAICS antibody (ab76404)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab76404 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: Use at a concentration of 1 µg/ml. Predicted molecular weight: 47 kDa.
ELISA titre using peptide based assay:1:312500
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Pathway
Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2.
Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (carboxylase route): step 1/1.
Sequence similarities
In the N-terminal section; belongs to the SAICAR synthetase family.
In the C-terminal section; belongs to the AIR carboxylase family.
Target information above from: UniProt accessionP22234
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- ADE2 antibody
- ADE2H1 antibody
- AIR carboxylase antibody
see all
Database links
- Entrez Gene: 10606 Human
- Entrez Gene: 67054 Mouse
- Entrez Gene: 140946 Rat
- Omim: 172439 Human
- SwissProt: P22234 Human
- SwissProt: Q9DCL9 Mouse
- SwissProt: P51583 Rat
- Unigene: 518774 Human
see all
Anti-PAICS antibody images:
Western blot - PAICS antibody (ab76404)
Anti-PAICS antibody (ab76404) at 1 µg/ml + Fetal heart lysate at 10 µg
Secondary
HRP conjugated anti-Rabbit IgG at 1/50000 dilution
Predicted band size : 47 kDa
Observed band size : 47 kDa
References for Anti-PAICS antibody (ab76404)
ab76404 has not yet been referenced specifically in any publications.
Publishing research using ab76404? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"