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Products:Epigenetics and Nuclear Signaling >> DNA / RNA >> Translation >> Regulation
Overview
Product name
PAIP2 peptide
See all PAIP2 products (3) ...
Protein description
Synthetic peptide derived from within residues 1 - 100 of Human PAIP2.(Note: the amino acid sequence is proprietary)This peptide was used as an immunogen for ab33455 - PAIP2 antibody.
Protein length
127 amino acids
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Information available upon request.
Concentration
Concentration information loading...
Research areas
Epigenetics and Nuclear Signaling >> DNA / RNA >> Translation >> Regulation
Applications
Application notes
This peptide can be used with studies using ab33455.
Protein info
Relevance
PAIP2 acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. It displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization (referenced from Swiss-Prot).
Cellular localization
Cytoplasmic
References for PAIP2 peptide (ab36582)
ab36582 has not yet been referenced specifically in any publications.
Publishing research using ab36582? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"