Overview

  • Product name
  • Description
    Goat polyclonal to PATJ
  • Host species
    Goat
  • Tested applications
    Suitable for: ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rabbit, Horse, Chicken, Cow, Dog, Turkey, Chimpanzee, Macaque monkey, Common marmoset, Orangutan, Bat
  • Immunogen

    Synthetic peptide:

    PENPATDKLQVLQ-C

    , corresponding to N terminal amino acids 2-14 of Human PATJ (NP_795352.2).

  • Positive control
    • Human testis tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab134784 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/32000.
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Relevance
    PATJ contains multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. PATJ localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors.
  • Cellular localization
    Membrane. Cell junction; tight junction. Apical cell membrane. Note: Localized in the paranodal region of myelinating Schwann cells. Membrane-associated. Localizes to tight junctions in epithelial cells. Also found at the apical plasma membrane.
  • Database links
  • Alternative names
    • Channel interacting PDZ domain protein antibody
    • Cipp antibody
    • FLJ26982 antibody
    • hINADL antibody
    • Inactivation no after potential D like protein antibody
    • INAD like antibody
    • InaD like Drosophila antibody
    • INAD like protein antibody
    • INADL antibody
    • INADL protein antibody
    • PALS 1 associated tight junction protein antibody
    • PALS1 associated tight junction protein antibody
    • PATJ antibody
    • PDZ domain protein antibody
    • PDZ domain protein Drosophila inaD like antibody
    • Post synaptic density 95 / discs large / zonula occludens 1 domain protein antibody
    • Protein associated to tight junctions antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin- embedded Human testis tissue labelling PATJ with ab134784 at 3.75ug/ml

References

ab134784 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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