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Overview
Product name
Anti-PAX5 antibody, prediluted
See all PAX5 products (15) ...
Description
Rabbit polyclonal to PAX5, prediluted
Tested applications
IHC-Pmore details
Cross reactivity
Reacts with
Cat, Human
Predicted to work with
Mouse, Rat
Immunogen
Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Human) (C terminal).
Positive control
Tonsil.
Properties
Form
Prediluted
Storage instructions
Store at +4°C.
Storage buffer
Preservative: 0.1% Sodium Azide
Constituents: 1% BSA, 50mM Tris, pH 7.6
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> Developmental Families >> PAX
Neuroscience >> Neurology process >> Neurogenesis
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PAX5 antibody, prediluted (ab15166)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab15166 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-P: Use at an assay dependent dilution. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
Target
Function
May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.
Involvement in disease
Note=A chromosomal aberration involving PAX5 is a cause of acute lymphoblastic leukemia. Translocation t(9;18)(p13;q11.2) with ZNF521. Translocation t(9;3)(p13;p14.1) with FOXP1. Translocation t(9;12)(p13;p13) with ETV6.
Sequence similarities
Contains 1 paired domain.
Developmental stage
Expressed at early B-cell differentiation, in the developing CNS and in adult testis.
Post-translational
modifications
O-glycosylated.
Cellular localization
Nucleus.
Target information above from: UniProt accessionQ02548
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- B cell lineage specific activator antibody
- B cell lineage specific activator protein antibody
- B cell specific activator protein antibody
see all
Database links
- Entrez Gene: 5079 Human
- Entrez Gene: 18507 Mouse
- Omim: 167414 Human
- SwissProt: Q02548 Human
- SwissProt: Q02650 Mouse
- Unigene: 654464 Human
- Unigene: 439659 Mouse
Anti-PAX5 antibody, prediluted images:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PAX5 antibody, prediluted (ab15166)
ab15166 staining PAX5 in human tonsil by Immunohistochemistry (Formalin/ PFA fixed paraffin embedded tissue sections).
References for Anti-PAX5 antibody, prediluted (ab15166)
ab15166 has not yet been referenced specifically in any publications.
Publishing research using ab15166? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"