You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Overview

  • Product namePAX7 peptideSee all PAX7 proteins and peptides ...
  • Protein descriptionSynthetic peptide derived from within residues 500 to the C-terminus of Human PAX7.(Note: the amino acid sequence is proprietary)This peptide was used as an immunogen for ab34360 - PAX7 antibody.
  • Protein length520 amino acids

    • Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferInformation available upon request.
  • Concentration information loading...
  • Research Areas

    • Applications

  • Application notesThis peptide can be used with studies using ab34360.

    • Protein info

    • Alternative names
        FLJ37460HUP1OTTHUMP00000002534
        Paired box 7Paired box gene 7Paired box homeotic gene 7Paired box protein Pax-7Paired domain gene 7Paired domain gene HuP1Pax7PAX7 transcriptional factorPAX7/FKHR fusion gene, includedPAX7_HUMANPAX7BRGD1564360
      see all
  • FunctionProbable transcription factor. May have a role in myogenesis.
  • Involvement in diseaseDefects in PAX7 are a cause of rhabdomyosarcoma type 2 (RMS2) [MIM:268220]. It is a form of rhabdomyosarcoma, a highly malignant tumor of striated muscle derived from primitive mesenchimal cells and exhibiting differentiation along rhabdomyoblastic lines. Rhabdomyosarcoma is one of the most frequently occurring soft tissue sarcomas and the most common in children. It occurs in four forms: alveolar, pleomorphic, embryonal and botryoidal rhabdomyosarcomas. Note=A chromosomal aberration involving PAX7 is found in rhabdomyosarcoma. Translocation t(1;13)(p36;q14) with FOXO1. The resulting protein is a transcriptional activator.
  • Sequence similaritiesBelongs to the paired homeobox family.
    Contains 1 homeobox DNA-binding domain.
    Contains 1 paired domain.
  • Cellular localizationNucleus.

    • Target information above from: UniProt accession P23759 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for PAX7 peptide (ab37576)

    ab37576 has not yet been referenced specifically in any publications.

    Publishing research using ab37576 ? Please let us know so that we can cite the reference in this datasheet

    Product Wall

    Submit an Abreview for ab37576 Submit a Question for ab37576

    Displaying 1 - 1 of 1 results for Abreviews and Q&A

    10
    Votes: Highest First

    send information about conjugation kits

    Thank you for contacting us.

    Unfortunately, we do not carry a conjugated antibody for PAX7.

    However, we carry a number of easy-to-use conjugation kits. Please see the link for the list of kits we carry:

    http://www.abcam.com/...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"