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Product name
Anti-PBEF antibody
See all PBEF products (12) ...
Description
Rabbit polyclonal to PBEF
Tested applications
IHC-Pmore details
Cross reactivity
Reacts with
Human
Immunogen
Synthetic peptide, corresponding to a region within the amino acids 400-450 of Human PBEF (SwissProt: P43490)
Positive control
Human fetal membrane.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.09% Sodium Azide
Constituents: 0.1% BSA, Tris buffered saline
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Metabolism >> Types of disease >> Cancer
Metabolism >> Pathways and Processes >> Metabolism processes >> Hypoxia
Neuroscience >> Neurology process >> Metabolism
Signal Transduction >> Growth Factors/Hormones >> Insulin / Insulin-like
Immunology >> Innate Immunity >> Cytokines >> Other
Immunology >> Adaptive Immunity >> B Cells >> Non-CD
Cardiovascular >> Blood >> Serum Proteins
Cardiovascular >> Hypoxia >> Hypoxia-Regulated
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PBEF antibody (ab84092)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab84092 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
IHC-P
Application notes
IHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway.
Tissue specificity
Expressed in large amounts in bone marrow, liver tissue, and muscle. Also present in heart, placenta, lung, and kidney tissues.
Pathway
Cofactor biosynthesis; NAD(+) biosynthesis; nicotinamide D-ribonucleotide from 5-phospho-alpha-D-ribose 1-diphosphate and nicotinamide: step 1/1.
Sequence similarities
Belongs to the NAPRTase family.
Cellular localization
Cytoplasm.
Target information above from: UniProt accessionP43490
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- AI480535 antibody
- 1110035O14Rik antibody
- AI314458 antibody
see all
Database links
- Entrez Gene: 10135 Human
- Omim: 608764 Human
- SwissProt: P43490 Human
- Unigene: 489615 Human
Anti-PBEF antibody images:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PBEF antibody (ab84092)
Detection of Human PBEF by Immunohistochemistry.Sample: FFPE section of Human fetal membrane.Antibody: ab84092 used at a dilution of 1/500.Detection: DAB.
References for Anti-PBEF antibody (ab84092)
ab84092 has not yet been referenced specifically in any publications.
Publishing research using ab84092? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"