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Overview

  • Product namePBK protein (His tag)See all PBK proteins and peptides ...
  • Protein descriptionRecombinant full length Human PBK (amino acids 1-322) with an N terminal His tag; 346 amino acids with a predicted MWt of 38.6 kDa including tag (Q96KB5).
  • Uniprot accessionQ96KB5
  • Molecular weight38.600kDa inclusive of tags
  • Protein length322 amino acids
  • Expression hostE. coli

    • Properties

  • Purity> 95 % by SDS-PAGE
  • Purification notesab123196 is purified using conventional chromatography techniques.
  • Mass spectrometryMALDI-TOF
  • E.C. Number2.7.12.2
  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferpH: 7.20
    Constituents: 0.02% DTT, 0.32% Tris HCl, 10% Glycerol, 0.58% Sodium chloride
  • Concentration information loading...
  • Sequence notesMGSSHHHHHH SSGLVPRGSH MGSHMEGISN FKTPSKLSEK KKSVLCSTPT INIPASPFMQ KLGFGTGVNV YLMKRSPRGL SHSPWAVKKI NPICNDHYRS VYQKRLMDEA KILKSLHHPN IVGYRAFTEA NDGSLCLAME YGGEKSLNDL IEERYKASQD PFPAAIILKV ALNMARGLKY LHQEKKLLHG DIKSSNVVIK GDFETIKICD VGVSLPLDEN MTVTDPEACY IGTEPWKPKE AVEENGVITD KADIFAFGLT LWEMMTLSIP HINLSNDDDD EDKTFDESDF DDEAYYAALG TRPPINMEEL DESYQKVIEL FSVCTNEDPK DRPSAAHIVE ALETDV
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab123196 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent concentration.
    MS MS: Use at an assay dependent concentration.

    Protein info

    • Alternative names
        Cancer/testis antigen 84CT84FLJ14385
        Lymphokine activated killer T cell originated protein kinaseLymphokine-activated killer T-cell-originated protein kinaseMAPKK like protein kinaseMAPKK-like protein kinaseNori 3Nori-3Nori3PBKPDZ binding kinasePDZ-binding kinaseSerine/threonine protein kinaseSpermatogenesis related protein kinaseSpermatogenesis-related protein kinaseSPKT LAK cell originated protein kinaseT-LAK cell-originated protein kinaseTOPKTOPK_HUMAN
      see all
  • FunctionPhosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.
  • Tissue specificityExpressed in the testis and placenta. In the testis, restrictedly expressed in outer cell layer of seminiferous tubules.
  • Sequence similaritiesBelongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase kinase subfamily.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications    Phosphorylated; in a cell-cycle dependent manner at mitosis.

    • Target information above from: UniProt accession Q96KB5 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    PBK protein (His tag) images

    • SDS-PAGE - PBK protein (His tag) (ab123196)
      SDS-PAGE - PBK protein (His tag) (ab123196)
      15% SDS-PAGE showing ab123196 (3µg).
      (Molecular size on SDS-PAGE will appear higher).

    References for PBK protein (His tag) (ab123196)

    ab123196 has not yet been referenced specifically in any publications.

    Publishing research using ab123196 ? Please let us know so that we can cite the reference in this datasheet

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