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Products:Epigenetics and Nuclear Signaling >> DNA / RNA >> Translation >> ER Translocation
Overview
Product name
PC6 peptide (Homp-P domain)
See all PC6 products (3) ...
Protein description
Synthetic peptide PC6. (Note: the amino acid sequence is proprietary) This peptide was used as an immunogen for ab40133 - PC6 antibody - Homp-P domain.
Properties
Purity
>95% by SDS-PAGE
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 0.001% Tween 20, 30mM HEPES, 2mM EDTA, 150mM Sodium chloride, pH 6.75
Concentration
Concentration information loading...
Applications
Show applications key
Our Abpromise guarantee covers the use of ab41414 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA
WB
Application notes
ELISA: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. This peptide can be used with studies using ab40133. Dilution optimised using Chromogenic detection. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Protein info
Function
Likely to represent a widespread endoprotease activity within the constitutive and regulated secretory pathway. Capable of cleavage at the RX(K/R)R consensus motif.
Tissue specificity
Expressed in T-lymphocytes.
Sequence similarities
Belongs to the peptidase S8 family.
Contains 1 homo B/P domain.
Contains 1 PLAC domain.
Domain
The propeptide domain acts as an intramolecular chaperone assisting the folding of the zymogen within the endoplasmic reticulum.
Cellular localization
Secreted.
Target information above from: UniProt accessionQ92824
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
References for PC6 peptide (Homp-P domain) (ab41414)
ab41414 has not yet been referenced specifically in any publications.
Publishing research using ab41414? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"