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Anti-PCSK9 antibody - Homo-B domain (ab42086)

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1 question for ab42086

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Question 1

Thursday 08-April-2010

Could you at least tell me whether it binds in the prodomain, catalytic domain or c-terminal domain?

ANSWER:

  

Thank you for your patience.

The nomenclature for the Homo-B domain comes from comparative alignments with the other members of the Proprptein Convertase family, notably PC-4. The Homo-B like domain is the carboxyterminal half of the PCKS protein. The epitope for ab42086 is close to the carboxyterminal end of the PC-9 protein.

I hope this helps.

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