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Product Name 

PCSK9 peptide (Homo-B domain)

Product type 

Proteins and Peptides

Peptide 

Synthetic peptide PCSK9.


This peptide was used as an immunogen for ab42086 - PCSK9 antibody - Homo-B domain.

Specificity 

We have a range of domain specific antibodies for this target. For a full list please see all PCSK9 antibodies

Tested applications 
(see key)

ELISA, WB

Application notes 
(see key)

Recommended dilutions
ELISA: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. This peptide can be used with studies using ab42086. Dilution optimised using Chromogenic detection. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Research areas 

Cell Biology >> Proteolysis / Ubiquitin >> Proteolytic enzymes >> Serine protease >> Proprotein Convertases
Signal Transduction >> Metabolism >> Lipid metabolism
Stem Cells >> Neural Stem Cells >> Intracellular
Cardiovascular >> Lipids / Lipoproteins >> Lipid Metabolism >> Cholesterol Metabolism
Signal Transduction >> Metabolism >> Amino Acids

Relevance 

PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. PCSK9 may function as a proprotein convertase. PCSK9 plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in PCSK9 gene have been associated with a third form of autosomal dominant familial hypercholesterolemia.

 

PCSK9 peptide (Homo-B domain) (ab44583)

Purity 

>95% by SDS-PAGE

Storage buffer 

Preservative: None
Constituents: 0.001% Tween 20, 30mM HEPES, 2mM EDTA, 150mM Sodium chloride, pH 6.75

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this PCSK9 peptide (Homo-B domain) is on this datasheet. But please do contact us if you would like any reassurance!


 

Search PubMed (MEDLINE) for references to PCSK9

 

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Corresponding Antibody for PCSK9 peptide (Homo-B domain)

ab42086

  

Rabbit polyclonal to PCSK9 - Homo-B domain

 

Other PCSK9 Antibodies

See all PCSK9 antibodies (6)...

 

PCSK9 peptide (Homo-B domain) - other tools:

Contact Abcam with a Technical Enquiry about PCSK9 peptide (Homo-B domain)

 

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