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Product Name 

PCSK9 peptide (Propeptide domain)

Product type 

Proteins and Peptides

Peptide 

Synthetic peptide PCSK9.


This peptide was used as an immunogen for ab42085 - PCSK9 antibody - Propeptide domain.

Specificity 

We have a range of domain specific antibodies for this target. For a full list please see all PCSK9 antibodies

Tested applications 
(see key)

ELISA, WB

Application notes 
(see key)

Recommended dilutions
ELISA: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. This peptide can be used with studies using ab42085. Dilution optimised using Chromogenic detection. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Research areas 

Cell Biology >> Proteolysis / Ubiquitin >> Proteolytic enzymes >> Serine protease >> Proprotein Convertases
Signal Transduction >> Metabolism >> Lipid metabolism
Stem Cells >> Neural Stem Cells >> Intracellular
Cardiovascular >> Lipids / Lipoproteins >> Lipid Metabolism >> Cholesterol Metabolism
Signal Transduction >> Metabolism >> Amino Acids

Relevance 

PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. PCSK9 may function as a proprotein convertase. PCSK9 plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in PCSK9 gene have been associated with a third form of autosomal dominant familial hypercholesterolemia.

 

Alternative names PCSK9 peptide (Propeptide domain) (ab44562)

Purity 

>95% by SDS-PAGE

Storage buffer 

Preservative: None
Constituents: 0.001% Tween 20, 30mM HEPES, 2mM EDTA, 150mM Sodium chloride, pH 6.75

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this PCSK9 peptide (Propeptide domain) is on this datasheet. But please do contact us if you would like any reassurance!


 

Search PubMed (MEDLINE) for references to PCSK9

 

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Corresponding Antibody for PCSK9 peptide (Propeptide domain)

ab42085

  

Rabbit polyclonal to PCSK9 - Propeptide domain

 

Other PCSK9 Antibodies

See all PCSK9 antibodies (6)...

 

PCSK9 peptide (Propeptide domain) - other tools:

Contact Abcam with a Technical Enquiry about PCSK9 peptide (Propeptide domain)

 

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