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Product name
PD 98059
Description
MEK1 inhibitor
Alternative names
- PD090859
Biological description
Inhibitor of MKK1 (MEK1).
Purity
> 99%
General notes
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Properties
Chemical name
2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one
Molecular Weight
267.28
Chemical structure
Molecular formula
C16H13NO3
CAS Number
167869-21-8
Solubility
Soluble in DMSO to 25 mM and in ethanol to 5 mM
PubChem identifier
0
Storage instructions
Store at room temperature.
Research areas
Biochemicals >> Pharmacology >> Enzymes >> Kinase >> MAP kinase >> Inhibitors
Biochemicals >> Chemical Type >> Biochemicals
References for PD 98059 (ab120234)
This product has been referenced in:
- Alessi DR et al. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 270:27489-94 (1995).Read more (PubMed: 7499206) »
- Dudley DT et al. A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc Natl Acad Sci U S A 92:7686-9 (1995).Read more (PubMed: 7644477) »
See all 2 publications for this product
Publishing research using ab120234? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"