Recombinant
RabMAb

Anti-PD1 antibody [EPR4877(2)] - BSA and Azide free (ab186928)

Overview

  • Product name
    Anti-PD1 antibody [EPR4877(2)] - BSA and Azide free
    See all PD1 primary antibodies
  • Description
    Rabbit monoclonal [EPR4877(2)] to PD1 - BSA and Azide free
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human PD1 aa 1-100. The exact sequence is proprietary.
    (Peptide available as ab173374)

  • Positive control
    • Human T cell lymphoma and Human tonsil tissues
  • General notes

    Please view the parent abID of this product, ab137132, for information on validated applications.

    Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab186928 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 1 µg/ml.

Please check the parent abID, ab137132, for a recommended dilution.

Target

  • Function
    Possible cell death inducer, in association with other factors.
  • Involvement in disease
    Genetic variation in PDCD1 is associated with susceptibility to systemic lupus erythematosus type 2 (SLEB2) [MIM:605218]. Systemic lupus erythematosus is a chronic, inflammatory and often febrile multisystemic disorder of connective tissue. It affects principally the skin, joints, kidneys and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system.
  • Sequence similarities
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Developmental stage
    Induced at programmed cell death.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD279 antibody
    • CD279 antigen antibody
    • hPD 1 antibody
    • hPD l antibody
    • hPD-1 antibody
    • hSLE1 antibody
    • PD 1 antibody
    • PD-1 antibody
    • PD1 antibody
    • PDCD 1 antibody
    • PDCD1 antibody
    • PDCD1_HUMAN antibody
    • Programmed cell death 1 antibody
    • Programmed cell death 1 protein antibody
    • Programmed cell death protein 1 antibody
    • Protein PD 1 antibody
    • Protein PD-1 antibody
    • SLEB2 antibody
    • Systemic lupus erythematosus susceptibility 2 antibody
    see all

Images

  • Immunohistochemistry (Paraffin-embedded sections) analysis of Human angioimmunoblastic T-cell lymphoma tissue labeling PD1 with ab186928 at 1/1000. Heat mediated antigen retrieval was perfomed using Tris/EDTA buffer pH 9. Anti-rabbit IgG H&L (HRP) (ab97051) was used as the secondary antibody at 1/500. Counterstained with hematoxylin.

  • Immunohistochemistry (Paraffin-embedded sections) analysis of Human tonsil tissue labeling PD1 with ab186928 at 1/1000. Heat mediated antigen retrieval was perfomed using Tris/EDTA buffer pH 9. Anti-rabbit IgG H&L (HRP) (ab97051) was used as the secondary antibody at 1/500. Counterstained with hematoxylin.

References

ab186928 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab186928.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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