Overview

  • Product namePD173955
  • Description
    Potent and selective abelson (Abl) kinase inhibitor
  • Biological descriptionPotent and selective abelson (Abl) kinase inhibitor. Inhibits both the active and inactive forms of Abl. Inhibits Src and Yes tyrosine kinases. Induces mitotic arrest. Shows antiproliferative effects.
  • Purity> 99%

Properties

  • Chemical name6-(2,6-Dichlorophenyl)-8-methyl-2-[[3-(methylthio)phenyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one
  • Molecular Weight443.35
  • Chemical structureChemical Structure
  • Molecular formulaC21H16Cl2N4OS
  • CAS Number260415-63-2
  • PubChem identifier447077
  • Storage instructionsStore at +4°C (desiccating conditions).
  • Solubility overviewSoluble in DMSO
  • Handling

    Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 12 months.

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  • SMILESCN1C2=NC(=NC=C2C=C(C1=O)C3=C(C=CC=C3Cl)Cl)NC4=CC(=CC=C4)SC
  • Source

    Synthetic

  • Research Areas

    References for PD173955 (ab142020)

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