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Anti-PDE3B antibody (ab42091)

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Overview

Product name

Anti-PDE3B antibody
See all PDE3B products (5) ...

Description

Goat polyclonal to PDE3B

Specificity

Does not cross react with PDE4A variants nor with any other PDEs.

Tested applications

IP, WBmore details

Cross reactivity

Reacts with

Mouse, Rat, Human

Immunogen

Synthetic peptide (Human) (selective for only PDE3B variant).

Properties

Form

Liquid

Storage instructions

Store at -20°C, Stable for 6 months at -20°C

Storage buffer

Antibody stabilization buffer, with preservatives, consisting of Hepes, NaCl, KCl, glycerol, BSA and chaotropic agents.

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Clonality

Polyclonal

Isotype

IgG

Research areas

Signal Transduction >> Metabolism >> Lipid metabolism
Signal Transduction >> Second Messenger >> Nucleotide Messenger >> cGMP
Signal Transduction >> Second Messenger >> Nucleotide Messenger >> cAMP

  • Western blot - PDE3B antibody (ab42091)Western blot - PDE3B antibody (ab42091) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab42091 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • IP

     IP: 1/200

    IP: 1/200

  • ShowHide1 Image

    WB

     WB: 1/500Detects a band ...Read more →

    WB: 1/500Detects a band of approximately 145 kDa (predicted molecular weight: 145 kDa).

Target

Function

Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism.

Tissue specificity

Abundant in adipose tissues.

Sequence similarities

Belongs to the cyclic nucleotide phosphodiesterase family. PDE3 subfamily.

Cellular localization

Membrane.

Target information above from: UniProt accessionQ13370 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • 5''-cyclic phosphodiesterase B antibody
  • adipocyte cAMP phosphodiesterase cGMP inhibited antibody
  • AI847709 antibody
  • cAMP Phosphodiesterase, adipocyte, cGMP-inhibited antibody
  • CGI-PDE B antibody
  • CGIP1 antibody
  • CGIPDE B antibody
  • cGIPDE1 antibody
  • cGMP inhibited 3 5 cyclic phosphodiesterase B antibody
  • CGMP inhibited cAMP phophodiesterase antibody
  • cGMP-inhibited 3'' antibody
  • cyclic GMP inhibited phosphodiesterase B antibody
  • Cyclic GMP-inhibited phosphodiesterase B antibody
  • Cyclic nucleotide phosphodiesterase antibody
  • HcGIP1 antibody
  • HcGIP1, rat, homolog of antibody
  • Pde3b antibody
  • PDE3B_HUMAN antibody
  • Phosphodiesterase 3B cGMP inhibited antibody
see all

Database links

see all

Anti-PDE3B antibody images:

  Western blot - PDE3B antibody (ab42091)

Western blot - PDE3B antibody (ab42091)

Anti-PDE3B antibody (ab42091) at 1/250 dilution + PDE3B protein

Predicted band size : 145 kDa
Observed band size : 145 kDa

References for Anti-PDE3B antibody (ab42091)

ab42091 has not yet been referenced specifically in any publications.

Publishing research using ab42091? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"