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Products:Signal Transduction >> Second Messenger >> Nucleotide Messenger >> cAMP
Overview
Product name
Anti-PDE3B antibody
See all PDE3B products (5) ...
Description
Mouse monoclonal to PDE3B
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Recombinant fragment: LTPFPGFYPC SEIEDPAEKG DRKLNKGLNR NSLPTPQLRR SSGTSGLLPV EQSSRWDRNN GKRPHQEFGI SSQGCYLNGP FNSNLLTIPK QRSSSVSLTH , corresponding to amino acids 401-501 of Human PDE3B
LTPFPGFYPC SEIEDPAEKG DRKLNKGLNR NSLPTPQLRR SSGTSGLLPV EQSSRWDRNN GKRPHQEFGI SSQGCYLNGP FNSNLLTIPK QRSSSVSLTH
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG2a
Light chain type
kappa
Research areas
Signal Transduction >> Metabolism >> Lipid metabolism
Signal Transduction >> Second Messenger >> Nucleotide Messenger >> cGMP
Signal Transduction >> Second Messenger >> Nucleotide Messenger >> cAMP
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Western blot - PDE3B antibody (ab55558)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab55558 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: Use at a concentration of 1-5 µg/ml.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism.
Tissue specificity
Abundant in adipose tissues.
Sequence similarities
Belongs to the cyclic nucleotide phosphodiesterase family. PDE3 subfamily.
Cellular localization
Membrane.
Target information above from: UniProt accessionQ13370
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- 5''-cyclic phosphodiesterase B antibody
- Adipocyte cAMP phosphodiesterase cGMP inhibited antibody
- AI847709 antibody
see all
Database links
- Entrez Gene: 5140 Human
- Omim: 602047 Human
- SwissProt: Q13370 Human
- Unigene: 445711 Human
Anti-PDE3B antibody images:
Western blot - PDE3B antibody (ab55558)
Western blot against tagged recombinant protein immunogen using ab55558 PDE3B antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa
References for Anti-PDE3B antibody (ab55558)
ab55558 has not yet been referenced specifically in any publications.
Publishing research using ab55558? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"