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Products:Signal Transduction >> Second Messenger >> Nucleotide Messenger >> cAMP
Overview
Product name
Anti-PDE6 delta antibody
See all PDE6 delta products (3) ...
Description
Mouse monoclonal to PDE6 delta
Tested applications
WB, ICC/IFmore details
Cross reactivity
Reacts with
Human
Immunogen
Recombinant full length protein, corresponding to amino acids 1-151 of Human PDE6D
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG2b
Light chain type
kappa
Research areas
Neuroscience >> Sensory System >> Visual system
Signal Transduction >> Second Messenger >> Nucleotide Messenger >> cGMP
Signal Transduction >> Second Messenger >> Nucleotide Messenger >> cAMP
Applications
Show applications key
Our Abpromise guarantee covers the use of ab55563 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 1 - 5 µg/ml.Predicted molecular weight: 17 kDa.
ICC/IF: Use a concentration of 10 µg/ml
Target
Function
Acts as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude and does so by decreasing the nucleotide dissociation rate. Stabilizes Arl3-GTP by decreasing the nucleotide dissociation.
Tissue specificity
Retina.
Sequence similarities
Belongs to the PDE6D/unc-119 family.
Target information above from: UniProt accessionO43924
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- 5''-cyclic phosphodiesterase subunit delta antibody
- GMP PDE delta antibody
- GMP-PDE delta antibody
see all
Database links
- Entrez Gene: 5147 Human
- Omim: 602676 Human
- SwissProt: O43924 Human
- Unigene: 516808 Human
Anti-PDE6 delta antibody images:
Western blot - PDE6D antibody (ab55563)
PDE6D antibody (ab55563) at 1ug/lane + HeLa cell lysate at 25ug/lane.
Immunocytochemistry/ Immunofluorescence-PDE6 delta antibody(ab55563)
ab55563 at 10 ug/ml staining PDE6 delta in human Hella cells by Immunocytochemistry/ Immunofluorescence.
References for Anti-PDE6 delta antibody (ab55563)
ab55563 has not yet been referenced specifically in any publications.
Publishing research using ab55563? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"