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Anti-PDGF BB antibody (ab10845)

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1 question for ab10845

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Question 1

Tuesday 12-July-2005

Customer is using this antibody in neutralization experiments with rat smooth muscle cells. Is there a neutralization protocol available for this antibody?

ANSWER:

 

Thank you for your enquiry. Unfortunately, a neutralization protocol is not available for this antibody. Ab10845 will neutralize the biological activity of recombinant human PDGF BB. It will also neutralize the activity of recombinant human-AB, natural human PDGF, rat PDGF BB, and porcine PDGF BB. It will neutralize the activity of recombinant human PDGF AA at 50-100 fold higher IgG concentration. The ND50 is approximately 0.025- 0.2 µg/ml.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"