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Product Name
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PDGF BB antibody
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See all PDGF BB antibodies (9)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to PDGF BB
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Immunogen
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Synthetic peptide: TEVFEISRRLIDRTNA, corresponding to amino acids 101-116 of PDGF BB
BLAST 'TEVFEISRRLIDRTNA' with  or 
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Reacts with
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Hu, Rat
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Predicted to react
(species key)
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Cat, Dog, Shp
(Due to sequence homology)
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Tested applications
(see key)
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ICC, IHC-P, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ICC (IF): Use at a concentration of 1 - 5 µg/ml.
IHC-P: Use at a concentration of 1 - 10 µg/ml.
WB: Use at a concentration of 1 - 5 µg/ml. Predicted molecular weight: 27 kDa.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Mesenchymal cells.
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Cellular localization
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Cytoplasmic
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Research areas
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Cancer >> Cancer Metabolism >> Response to hypoxia
Developmental Biology >> Organogenesis >> Angiogenesis and vasculogenesis
Cardiovascular >> Atherosclerosis >> Vascular Inflammation >> Inflammatory mediators
Cancer >> Growth factors >> PDGF
Signal Transduction >> Growth Factors/Hormones >> PDGF
Cardiovascular >> Blood >> Serum Proteins
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Relevance
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Platelet Derived Growth Factor (PDGF) is the major serum mitogen for cells of mesenchymal origin in humans. The biologically active protein is a dimer composed of two related polypeptides designated A and B, the dimers being connected by disulfide bonds. The PDGF protein has been implicated both directly as well as indirectly in several pathological states including neoplasia, arthritis, arteriosclerosis and bone marrow sclerosis.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Storage buffer
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Preservative: 0.1% Sodium Azide
Constituents: 0.2% Gelatin, 0.05M Sodium phosphate Material safety datasheets (MSDS) for this product:
Sodium Azide MSDS
Sodium Phosphate MSDS
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Form
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Liquid
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Concentration
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0.100 mg/ml
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Storage instructions
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Store at +4°C. Do not freeze.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this PDGF BB antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to PDGF BB
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PDGF BB antibody - more information
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