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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PDGF BB antibody (ab21234)
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Product Name
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PDGF BB antibody
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See all PDGF BB antibodies (9)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to PDGF BB
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Immunogen
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Synthetic peptide: TEVFEISRRL IDRTNA, corresponding to amino acids 101-116 of Human PDGF B.
BLAST 'TEVFEISRRL IDRTNA' with  or 
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Reacts with
(species key)
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Hu, Ms, Rat, Cat, Cow, Dog, Hm, Shp
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Specificity
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This antibody is specific for b form and reacts with PDGF (AB) and PDGF (BB) protein.
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Tested applications
(see key)
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IHC-P
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Abreviews
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Application notes
(see key)
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Recommended dilutions
IHC-P: Use at an assay dependent dilution. Perform heat mediated antigen retrieval with 10 mM citrate buffer, pH 6.0 before commencing with IHC staining protocol. Incubate for 30 minutes at room temperature.
ABC method: Use at a dilution of 1:50-1:100.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Angiosarcoma
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Cellular localization
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Cytoplasmic
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Research areas
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Cancer >> Cancer Metabolism >> Response to hypoxia
Developmental Biology >> Organogenesis >> Angiogenesis and vasculogenesis
Cardiovascular >> Atherosclerosis >> Vascular Inflammation >> Inflammatory mediators
Cancer >> Growth factors >> PDGF
Signal Transduction >> Growth Factors/Hormones >> PDGF
Cardiovascular >> Blood >> Serum Proteins
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Relevance
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Platelet Derived Growth Factor (PDGF) is the major serum mitogen for cells of mesenchymal origin in humans. The biologically active protein is a dimer composed of two related polypeptides designated A and B, the dimers being connected by disulfide bonds. The PDGF protein has been implicated both directly as well as indirectly in several pathological states including neoplasia, arthritis, arteriosclerosis and bone marrow sclerosis.
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PDGF BB antibody (ab21234) |
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Whole antiserum
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Storage buffer
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Preservative: 0.05% Sodium Azide
Constituents: 1% BSA Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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Concentration not determined - why is this?
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Storage instructions
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Store at +4°C.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this PDGF BB antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for PDGF BB antibody images, references, products related to ab21234 and other tools.
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PDGF BB antibody images:
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 Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PDGF BB antibody (ab21234)
Formalin fixed paraffin embedded human angiosarcoma stained with PDGF B using ABC and AEC chromogen.
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Search PubMed (MEDLINE) for references to PDGF BB
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PDGF BB antibody - more information
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Customer reviews (feedback) regarding PDGF BB antibody |
Customer FAQs regarding PDGF BB antibody |
Protocols for PDGF BB antibody |
Price and availability of products related to PDGF BB antibody |
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PDGF BB antibody - related products:
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PDGF BB antibody - other tools:
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Contact Abcam with a Technical Enquiry about PDGF BB antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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