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PDGF BB protein (Active) (ab79746)

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Overview

Product name

PDGF BB protein (Active)
See all PDGF BB products (9) ...

Protein description

Recombinant Human PDGF BB protein, is a disulfide-linked homodimer of two full length B chains (amino acids 82-190); 218 total amino acids, 24.3kDa (SwissProt ID P01127).

Expression host

E. coli

Properties

Purity

>95% by SDS-PAGE

Purification notes

Purity is >98% by SDS-PAGE and HPLC analysis.

Form

Lyophilised

Storage instructions

Store at -20°C. Stable for 12 months at -20°C

Concentration

Concentration information loading...

Additional notes

Endotoxin Level: < 1EU per µg of PDGF BB as determined by the LAL method.

Research areas

Stem Cells >> Stem Cell Cytokines >> Recombinant Human
Cancer >> Cancer Metabolism >> Response to hypoxia
Developmental Biology >> Organogenesis >> Angiogenesis and vasculogenesis
Cardiovascular >> Atherosclerosis >> Vascular Inflammation >> Inflammatory mediators
Cancer >> Growth factors >> PDGF
Signal Transduction >> Growth Factors/Hormones >> PDGF
Cardiovascular >> Blood >> Serum Proteins

Applications

Show applications key

Our Abpromise guarantee covers the use of ab79746 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • SDS-PAGE

     

  • Functional Studies

     

Application notes

Biological Activity: The ED50 as determined by the dose-dependent stimulation of BALB/c 3T3 cells proliferation is < 1.0 ng/ml.
SDS-PAGE: Use at an assay dependent dilution.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Protein info

Target information above from: UniProt accessionP01127 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

References for PDGF BB protein (Active) (ab79746)

ab79746 has not yet been referenced specifically in any publications.

Publishing research using ab79746? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"